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George D. Demetri, Scott Antonia, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad III, Thomas F. DeLaney, Kristen N. Ganjoo, Martin J. Heslin, Raymond J. Hutchinson, John M. Kane III, G. Douglas Letson, Sean V. McGarry, Richard J. O'Donnell, I. Benjamin Paz, John D. Pfeifer, Raphael E. Pollock, R. Lor Randall, Richard F. Riedel, Karen D. Schupak, Herbert S. Schwartz, Katherine Thornton, Margaret von Mehren, and Jeffrey Wayne

risk for recurrence but otherwise have good performance status. 67 , 68 The Sarcoma Meta-Analysis Collaboration performed a meta-analysis of 14 randomized trials (1568 patients) comparing adjuvant chemotherapy with follow-up, and in some cases RT

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Omalkhair Abulkhair, Nagi Saghir, Lobna Sedky, Ahmed Saadedin, Heba Elzahwary, Neelam Siddiqui, Mervat Al Saleh, Fady Geara, Nuha Birido, Nadia Al-Eissa, Sana Al Sukhun, Huda Abdulkareem, Menar Mohamed Ayoub, Fawaz Deirawan, Salah Fayaz, Alaa Kandil, Sami Khatib, Mufid El-Mistiri, Dorria Salem, El Siah Hassan Sayd, Mohammed Jaloudi, Mohammad Jahanzeb, and William I. Gradishar

Systemic Adjuvant Treatment: Hormone Receptor–Positive/HER2-Negative Disease Recommendations: Adjuvant chemotherapy should be recommended for patients younger than 40 years. Furthermore, adjuvant chemotherapy is recommended for moderately

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Prashant Gabani, Emily Merfeld, Amar J. Srivastava, Ashley A. Weiner, Laura L. Ochoa, Dan Mullen, Maria A. Thomas, Julie A. Margenthaler, Amy E. Cyr, Lindsay L. Peterson, Michael J. Naughton, Cynthia Ma, and Imran Zoberi

Adjuvant chemotherapy was also administered in 46 patients (30.1%). A total of 73 patients (47.7%) underwent breast-conserving surgery, and 118 (77.1%) underwent axillary lymph node dissection. The rate of pCR was 29.4% (n=45). Most patients (81

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Angela M. Davies, Philip C. Mack, Primo N. Lara Jr., Derick H. Lau, Kathleen Danenberg, Paul H. Gumerlock, and David R. Gandara

advanced or metastatic NSCLC . J Clin Oncol 2003 ; 21 : 2658 – 2663 . 36 Mitsudomi T Yatabe Y Tada H . Lack of predictive value of p53, p27, Bcl2, HER2/neu, EGFR alterations for efficacy of postoperative adjuvant chemotherapy consisting of

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Sheshadri Madhusudhana, Michelle Gates, Daulath Singh, Punita Grover, Mahathi Indaram, and An-Lin Cheng

new cancer diagnosis and a curative-intent treatment plan including adjuvant chemotherapy, definitive chemotherapy, or definitive CRT were selected for study inclusion. Eligible diagnoses were lymphoma (stage I–IV), solid tumor malignancy after

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Ronald C. Chen, William U. Shipley, Jason A. Efstathiou, and Anthony L. Zietman

cystectomy and adjuvant chemotherapy . Urology 2009 ; 73 : 833 – 837 . 28. Hagan MP Winter KA Kaufman DS . RTOG 97-06: initial report of a phase I-II trial of selective bladder conservation using TURBT, twice-daily accelerated irradiation

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chemotherapy is preferred for these patients to aid resectability. If IORT is not available, additional 10-20 Gy external beam radiation and/or brachytherapy could be considered to a limited volume. The ending of “prior to adjuvant chemotherapy” removed

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continuum of care in metastatic colorectal cancer have resulted in a major improvement in median survival compared with 1996, and adjuvant chemotherapy for stage III colon cancer with FOLFOX and CapeOx has also improved survival. Further, discovery of

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James Sun, Brittany J. Mathias, Christine Laronga, Weihong Sun, Jun-Min Zhou, William J. Fulp, John V. Kiluk, and M. Catherine Lee

and were more likely to be treated with adjuvant chemotherapy (both P <.0001) ( supplemental eTable 1 , available with this article at JNCCN.org ). After CLND, 44 patients (22%) had an increase in nodal staging ( Table 3 ). Before CLND, 13 patients

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Melinda L. Telli and Ronald M. Witteles

years of adjuvant trastuzumab monotherapy initiated after the completion of (neo)adjuvant chemotherapy and adjuvant radiotherapy versus observation. BCIRG 006 (n = 3222) contained 3 arms, including AC followed by docetaxel, with or without 1 year of