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Antonio Di Meglio, Nancy U. Lin, Rachel A. Freedman, William T. Barry, Eric P. Winer, and Ines Vaz-Luis

day 1 of first-line treatment. Specifically, we examined (1) imaging modality used (chest/abdomen/pelvis CT, bone scan, 18 F-fluorodeoxyglucose [FDG]-PET/PET-CT, abdominal MRI, abdominal ultrasound, chest radiograph, spine MRI, head CT, brain MRI); (2

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Ryan M. Kahn, Sushmita Gordhandas, Emeline Aviki, and Kara Long Roche

deny coverage for individuals at risk. Patients, physicians, and advocacy groups have identified breast MRI in carriers of HBOC and colonoscopies for younger individuals with Lynch syndrome as the most difficult services to obtain. 2 , 3 Difficulty in

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Gregory P. Kalemkerian, Billy W. Loo Jr, Wallace Akerley, Albert Attia, Michael Bassetti, Yanis Boumber, Roy Decker, M. Chris Dobelbower, Afshin Dowlati, Robert J. Downey, Charles Florsheim, Apar Kishor P. Ganti, John C. Grecula, Matthew A. Gubens, Christine L. Hann, James A. Hayman, Rebecca Suk Heist, Marianna Koczywas, Robert E. Merritt, Nisha Mohindra, Julian Molina, Cesar A. Moran, Daniel Morgensztern, Saraswati Pokharel, David C. Portnoy, Deborah Rhodes, Chad Rusthoven, Jacob Sands, Rafael Santana-Davila, Charles C. Williams Jr, Karin G. Hoffmann, and Miranda Hughes

fractionation schemes. The survival advantage of PCI was recently challenged by a randomized phase III Japanese trial of 224 patients with extensive-stage SCLC. 25 Patients were required to have an MRI before PCI to confirm the absence of brain metastases and

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clinical response signals in a broad array of solid tumors Evaluate whether dynamic contrast-enhanced MRI, to determine the degree of vascular permeability, and PET scan, to delineate tumor viability and glucose uptake, are able to predict major

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Kevin S. Scher, Juan-Sebastian Saldivar, Michael Fishbein, Alberto Marchevsky, and Karen L. Reckamp

fluorodeoxyglucose uptake in the right upper lobe mass and the right hilar and subcarinal regions. MRI of the brain in February 2010 was negative. She underwent an endobronchial ultrasound biopsy of a subcarinal node, which was positive for adenocarcinoma. Concurrent

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Matthew H. Kulke, Manisha H. Shah, Al B. Benson III, Emily Bergsland, Jordan D. Berlin, Lawrence S. Blaszkowsky, Lyska Emerson, Paul F. Engstrom, Paul Fanta, Thomas Giordano, Whitney S. Goldner, Thorvardur R. Halfdanarson, Martin J. Heslin, Fouad Kandeel, Pamela L. Kunz, Boris W. Kuvshinoff II, Christopher Lieu, Jeffrey F. Moley, Gitonga Munene, Venu G. Pillarisetty, Leonard Saltz, Julie Ann Sosa, Jonathan R. Strosberg, Jean-Nicolas Vauthey, Christopher Wolfgang, James C. Yao, Jennifer Burns, and Deborah Freedman-Cass

used techniques include CT and MRI. NETs of the gastrointestinal tract and lungs are highly vascular and can appear isodense with liver on conventional CT scan, depending on contrast phase. Multiphase CT or MRI scans should therefore be used for

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Jamie E. Flerlage, Susan M. Hiniker, Saro Armenian, Ellen C. Benya, Adam J. Bobbey, Vivian Chang, Stacy Cooper, Don W. Coulter, Branko Cuglievan, Bradford S. Hoppe, Leidy Isenalumhe, Kara Kelly, Leslie Kersun, Adam J. Lamble, Nicole A. Larrier, Jeffrey Magee, Kwadwo Oduro, Martha Pacheco, Anita P. Price, Kenneth B. Roberts, Christine M. Smith, Aliyah R. Sohani, Erin M. Trovillion, Emily Walling, Ana C. Xavier, Jennifer L. Burns, and Mallory Campbell

and 2 of 2, pages 745 and 746 in the algorithm). For staging and risk assessment, diagnostic imaging should be done before initiating chemotherapy or steroids whenever possible including: PET/CT or PET/MRI scans (whole-body); diagnostic contrast

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Lara Franziska Stolzenbach, Giuseppe Rosiello, Angela Pecoraro, Carlotta Palumbo, Stefano Luzzago, Marina Deuker, Zhe Tian, Anne-Sophie Knipper, Raisa Pompe, Kevin C. Zorn, Shahrokh F. Shariat, Felix K.H. Chun, Markus Graefen, Fred Saad, and Pierre I. Karakiewicz

profile. Fourth, we could not account for the use of additional staging tools, such as MRI. It is possible that the rates of prostate MRI have increased over time and approximate MRI use in prospective trials. However, it is unlikely that the follow-up of

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Ling-Long Tang, Yu-Pei Chen, Yan-Ping Mao, Zi-Xian Wang, Rui Guo, Lei Chen, Li Tian, Ai-Hua Lin, Li Li, Ying Sun, and Jun Ma

imaging modalities, such as MRI and PET scanning, have made it possible to measure tumor volume and extension more precisely in NPC. Additionally, developments in radiation technology, such as intensity-modulated radiotherapy (IMRT), have improved tumor

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NCCN Guidelines Insights: Rectal Cancer, Version 6.2020

Featured Updates to the NCCN Guidelines

Al B. Benson III, Alan P. Venook, Mahmoud M. Al-Hawary, Mustafa A. Arain, Yi-Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, Andrew Gunn, Sarah Hoffe, Joleen Hubbard, Steven Hunt, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A. Messersmith, Jeffrey Meyerhardt, Eric D. Miller, Mary F. Mulcahy, Steven Nurkin, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Alyse Johnson-Chilla, and Lisa A. Gurski

body habitus (ie, a measured distance of 12 cm from the anal verge would yield very different anatomic features in a patient who is 4 feet tall compared with one who is 7 feet tall). Furthermore, the panel considers MRI to be a superior tool compared