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Kelsey C. Stoltzfus, Biyi Shen, Leila Tchelebi, Daniel M. Trifiletti, Niraj J. Gusani, Vonn Walter, Ming Wang, and Nicholas G. Zaorsky

recommendations in the guidelines for other cancers, including breast and uterine, which are primarily treated with surgery. 4 Furthermore, previous studies analyzing facility volume are heterogeneous, with differing patient populations, outcome measures, and

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Christopher M. Booth, Sulaiman Nanji, Xuejiao Wei, Yingwei Peng, James J. Biagi, Timothy P. Hanna, Monika K. Krzyzanowska, and William J. Mackillop

during 2000–2008. The OCR does not capture stage of disease for all patients; therefore, we obtained surgical pathology reports for a random sample of 25% of cases. Reports were not available for patients with surgery in 2005; therefore, the study cohort

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Shiva Kumar R. Mukkamalla, Hussain M. Naseri, Byung M. Kim, Steven C. Katz, and Vincent A. Armenio

), moderately differentiated (grade II), poorly differentiated (grade III), undifferentiated/anaplastic (grade IV), or unknown. Based on surgery and radiation information in the SEER database, we redefined treatment types into unknown, no treatment, surgery only

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Romy M. van Amelsfoort, Iris Walraven, Jacobien Kieffer, Edwin P.M. Jansen, Annemieke Cats, Nicole C.T. van Grieken, Elma Meershoek-Klein Kranenbarg, Hein Putter, Johanna W. van Sandick, Karolina Sikorska, Cornelis J.H. van de Velde, Neil K. Aaronson, Marcel Verheij, and on behalf of the CRITICS Investigators

Background Gastric cancer is the fifth most common malignancy worldwide and the fourth most common cause of cancer-related death. 1 For patients from Western countries with gastric cancer, the prognosis remains poor after surgery alone, and

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Kari E. Hacker, Shitanshu Uppal, and Carolyn Johnston

borderline ovarian tumors (BOTs) and low-grade epithelial ovarian carcinomas (LG-EOCs) Assess the role of surgery, chemotherapy and fertility/hormonal preservation in the management of BOTs and LG-EOCs The International Federation of Gynecology and

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Stanley J. Miller, Murad Alam, James Andersen, Daniel Berg, Christopher K. Bichakjian, Glen Bowen, Richard T. Cheney, L. Frank Glass, Roy C. Grekin, Anne Kessinger, Nancy Y. Lee, Nanette Liegeois, Daniel D. Lydiatt, Jeff Michalski, William H. Morrison, Kishwer S. Nehal, Kelly C. Nelson, Paul Nghiem, Thomas Olencki, Clifford S. Perlis, E. William Rosenberg, Ashok R. Shaha, Marshall M. Urist, Linda C. Wang, and John A. Zic

carcinomas that develop in the high-risk mask area of the face are more likely to recur and metastasize than those that develop on the trunk and extremities. Adapted with permission from Swanson NA. Mohs surgery: technique, indications, applications, and

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Siddhartha Yadav, Sri Harsha Tella, Anuhya Kommalapati, Kristin Mara, Kritika Prasai, Mohamed Hamdy Mady, Mohamed Hassan, Rory L. Smoot, Sean P. Cleary, Mark J. Truty, Lewis R. Roberts, and Amit Mahipal

gallbladder. Patient-related factors, such as age and functional status, are not included in the staging system. These factors and other laboratory parameters may be helpful in the prognostication of patients with GBC who are not candidates for surgery. 7 , 8

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Richard Li, Wei-Hsien Hou, Joseph Chao, Yanghee Woo, Scott Glaser, Arya Amini, Rebecca A. Nelson, and Yi-Jen Chen

dissection, has been established as the primary curative treatment modality for locally advanced gastric cancer. 3 , 4 Perioperative chemotherapy, adjuvant chemotherapy, or adjuvant chemoradiation (CRT) are given in conjunction with surgery based on data

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NCCN Guidelines® Insights: Breast Cancer, Version 4.2021

Featured Updates to the NCCN Guidelines

William J. Gradishar, Meena S. Moran, Jame Abraham, Rebecca Aft, Doreen Agnese, Kimberly H. Allison, Sarah L. Blair, Harold J. Burstein, Chau Dang, Anthony D. Elias, Sharon H. Giordano, Matthew P. Goetz, Lori J. Goldstein, Sara A. Hurvitz, Steven J. Isakoff, Rachel C. Jankowitz, Sara H. Javid, Jairam Krishnamurthy, Marilyn Leitch, Janice Lyons, Jennifer Matro, Ingrid A. Mayer, Joanne Mortimer, Ruth M. O'Regan, Sameer A. Patel, Lori J. Pierce, Hope S. Rugo, Amy Sitapati, Karen Lisa Smith, Mary Lou Smith, Hatem Soliman, Erica M. Stringer-Reasor, Melinda L. Telli, John H. Ward, Kari B. Wisinski, Jessica S. Young, Jennifer L. Burns, and Rashmi Kumar

developed by a multidisciplinary panel of representatives from NCCN Member Institutions with breast cancer–focused expertise in the fields of medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy

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Hillary Johnson-Jahangir, William Sherman, and Désirée Ratner

metastasis, because the lung is the most common site of spread. 6 – 8 Surgical excision with careful margin evaluation is the preferred treatment for DFSP. Low recurrence rates have been shown after Mohs micrographic surgery (MMS) or wide local excision