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molecular biology and genomic profiling have led to the identification of several genetic aberrations and tumor characteristics that allow for distinct subgroups of metastatic CRC (mCRC) with both prognostic and predictive implications. One of these

first evidence of treatment ≥4 months from their advanced diagnosis date. Patient attrition is shown in supplemental eTable 1 (available with this article at JNCCN.org ). Construction of Variables Clinical characteristics included demographics

. Research staff collected information about cancer diagnosis, oral therapy type, and other clinical characteristics from the EHR. Electronic Adherence Monitoring Participants were asked to store their oral therapy medication in pill bottles with electronic

with patient characteristics, these profiles ensure that targeted therapies are selectively applied in delivering patient-centered care. A shining example of this has been the incorporation of trastuzumab for cancers that overexpress HER2, the use of

version 3.4.1 (R Foundation for Statistical Computing). All tests were 2-sided with a level of significance set at P <.05. Results Descriptive Characteristics Of all 210,100 patients treated with RP, 4,704 (2.2%), 17,785 (8.4%), and 11,040 (5

, potential eligible patients were first identified through the DCRA, and collaborators in each participating hospital were provided with their own patients registered in the DCRA. Subsequently, collaborators extended baseline characteristics and short

resection of the primary tumor, in consideration of postoperative recurrence and poor prognosis due to the high rate of occult cervical metastasis in early OSCC. 13 Because of the lack of consensus in characteristics, study populations, and patient

, characteristic imaging [LI-RADS 5] or histopathologic confirmation). 25 We excluded patients (1) with liver masses without characteristic imaging or histology, (2) for whom the date of HCC presentation and/or diagnosis could not be ascertained from the

.8% Hispanic, 7.8% African American, and 10.5% Asian. The characteristics of the study population are shown in Table 2 . Patients experienced a range of 16- to 77-week delays (median, 24 weeks) to initiating chemotherapy treatment. For 75% of patients, the

. Analyses were conducted using SAS 9.4 (SAS Institute Inc). Results Cohort Characteristics Of the 21,500 patients in the study cohort, 11,298 (52.5%) presented with metastatic disease, 3,092 (14.4%) were in the resectable group, and 7,110 (33.1%) were in the