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Tara M. Mackay, Lennart B. van Rijssen, Jurr O. Andriessen, Mustafa Suker, Geert-Jan Creemers, Ferry A. Eskens, Ignace H. de Hingh, Lonneke V. van de Poll-Franse, Mirjam A.G. Sprangers, Olivier R. Busch, Johanna W. Wilmink, Casper H. van Eijck, Marc G. Besselink, Hanneke W. van Laarhoven, and on behalf of the Dutch Pancreatic Cancer Group

postoperative clinical condition, adjuvant chemotherapy was offered. Palliative treatment was defined as any palliative systemic treatment of metastatic or locally advanced pancreatic or periampullary cancer. The start of treatment was defined as upfront surgery

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Sumanta K. Pal, Matthew I. Milowsky, and Elizabeth R. Plimack

approach to the disease. The utility of adjuvant chemotherapy after cystectomy remains highly contentious. Neoadjuvant therapy is also the subject of much discussion. Despite the existence of positive phase III data supporting this approach, it appears to

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David S. Ettinger, Wallace Akerley, Gerold Bepler, Matthew G. Blum, Andrew Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd L. Demmy, Apar Kishor P. Ganti, Ramaswamy Govindan, Frederic W. Grannis Jr., Thierry Jahan, Mohammad Jahanzeb, David H. Johnson, Anne Kessinger, Ritsuko Komaki, Feng-Ming Kong, Mark G. Kris, Lee M. Krug, Quynh-Thu Le, Inga T. Lennes, Renato Martins, Janis O'Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, George R. Simon, Scott J. Swanson, Douglas E. Wood, and Stephen C. Yang

-based therapy in a large group of patients with surgically resected NSCLC who participated in the International Adjuvant Lung Trial (IALT). In this study, only patients with low tumoral ERCC1 protein levels benefited from adjuvant chemotherapy (adjusted hazard

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Al B. Benson III, Alan P. Venook, Mahmoud M. Al-Hawary, Lynette Cederquist, Yi-Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Paul F. Engstrom, Ignacio Garrido-Laguna, Jean L. Grem, Axel Grothey, Howard S. Hochster, Sarah Hoffe, Steven Hunt, Ahmed Kamel, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A. Messersmith, Jeffrey Meyerhardt, Eric D. Miller, Mary F. Mulcahy, James D. Murphy, Steven Nurkin, Leonard Saltz, Sunil Sharma, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Evan Wuthrick, Kristina M. Gregory, and Deborah A. Freedman-Cass

, adjuvant chemotherapy. 10 Population and institutional studies have shown that adjuvant therapy may confer a survival advantage in some patients with resected colon cancer (eg, those with stage III or high-risk stage II disease). 11 – 14 Furthermore

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Elizabeth R. Kessler, Janet B. Kukreja, Christopher L. Geiger, and Stacy M. Fischer

, adjuvant therapy is occasionally considered. Studies examining adjuvant chemotherapy for bladder cancer have been limited by failure to accrue patients, and are thus underpowered for any definitive recommendations. These trials failed to fully accrue partly

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Arti Hurria, Ilene S. Browner, Harvey Jay Cohen, Crystal S. Denlinger, Mollie deShazo, Martine Extermann, Apar Kishor P. Ganti, Jimmie C. Holland, Holly M. Holmes, Mohana B. Karlekar, Nancy L. Keating, June McKoy, Bruno C. Medeiros, Ewa Mrozek, Tracey O’Connor, Stephen H. Petersdorf, Hope S. Rugo, Rebecca A. Silliman, William P. Tew, Louise C. Walter, Alva B. Weir III, and Tanya Wildes

associated with an increased risk of all-cause mortality (26.3% vs. 11.2%) among men with a history of coronary artery disease, CHF, or myocardial infarction after a median follow-up of 5.1 years. 45 In a randomized adjuvant chemotherapy trial of 3759

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Scott Ramsey and Veena Shankaran

-related expenses, which may not only cause significant anxiety but also may limit their ability to pay for basic necessities such as food and housing. 1 In a recent population-based survey of patients with CRC receiving adjuvant chemotherapy, 38% experienced

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Judd E. Cummings, J. Andrew Ellzey, and Robert K. Heck

-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults . J Clin Oncol 2003 ; 18 : 3423 – 3430 . 6. Link MP Goorin MA Miser AW . The effect of adjuvant chemotherapy on relapse

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Axel Grothey and Alan P. Venook

Hematology and Medical Oncology, Mayo Clinic Cancer Center, who described this study at the NCCN 23rd Annual Conference. “I believe we have the first important changes in adjuvant chemotherapy since 2004,” Dr. Grothey said, referring to the adoption of 6

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Erica L. Mayer, Nancy U. Lin, and Harold J. Burstein

; 354 : 809 – 820 . 38. Piccart-Gebhart MJ Procter M Leyland-Jones B . Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer . N Engl J Med 2005 ; 353 : 1659 – 1672 . 39. Slamon DJ Eiermann W Robert N . Phase