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Leena Gandhi and Bruce E. Johnson

. 2. Travis WD . Pathology of lung cancer . Clin Chest Med 2002 ; 23 : 65 – 81 , viii . 3. Addis BJ . Neuroendocrine differentiation in lung carcinoma . Thorax 1995 ; 50 : 113 – 115 . 4. Jiang SX Kameya T Asamura H

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Maxim Ivanov, Margarita Sharova, Andrea Olsen, Alexandra Lebedeva, Ekaterina Ignatova, Gerald Mouse, and Vladislav Mileyko

joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology . Genet Med 2015 ; 17 : 405 – 424 . 10.1038/gim.2015.30 25741868 3. Nykamp K , Anderson M , Powers M

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Joyce Y. Wong and Vernon K. Sondak

%, and a change in margin recommendation was made in 12%. Similarly, McGinnis et al. 56 evaluated more than 5000 primary melanocytic lesions seen in a pigmented lesion clinic, and reported an 11% discordance rate between the expert and initial pathology

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Mahmoud Al-Hawary

studies in complex pathologies such as pancreatic adenocarcinoma is the potential lack of completeness of the pertinent imaging findings or use of inappropriate terminology that is not mutually understandable by all members of the treating team. This

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Melinda L. Telli, Kathleen C. Horst, Alice E. Guardino, Frederick M. Dirbas, and Robert W. Carlson

: 454 – 459 . 9. Azzopardi JG Ahmed A Millis RR . Problems in breast pathology . Major Probl Pathol 1979 ; 11 : i - xvi , 1–466 . 10. Pietruszka M Barnes L . Cystosarcoma phyllodes: a clinicopathologic analysis of 42 cases

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NCCN Guidelines Insights: Breast Cancer, Version 3.2018

Featured Updates to the NCCN Guidelines

Matthew P. Goetz, William J. Gradishar, Benjamin O. Anderson, Jame Abraham, Rebecca Aft, Kimberly H. Allison, Sarah L. Blair, Harold J. Burstein, Chau Dang, Anthony D. Elias, William B. Farrar, Sharon H. Giordano, Lori J. Goldstein, Steven J. Isakoff, Janice Lyons, P. Kelly Marcom, Ingrid A. Mayer, Meena S. Moran, Joanne Mortimer, Ruth M. O'Regan, Sameer A. Patel, Lori J. Pierce, Elizabeth C. Reed, Hope S. Rugo, Amy Sitapati, Karen Lisa Smith, Mary Lou Smith, Hatem Soliman, Melinda L. Telli, John H. Ward, Jessica S. Young, Dorothy A. Shead, and Rashmi Kumar

medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy. In a recent version of these guidelines, the NCCN Breast Cancer Panel included updated recommendations for the use of multigene assays to

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Rishi Agarwal, Jiang Wang, Keith Wilson, William Barrett, and John C. Morris

demonstrated a paralyzed left vocal cord. The patient underwent an attempt at left thyroidectomy with tumor resection that also involved the esophagus and jugular vein, and a limited left neck dissection. Pathology was consistent with anaplastic

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Julia T. van Groningen, Pieter van Hagen, Rob A.E.M. Tollenaar, Jurriaan B. Tuynman, Perla J. Marang-van de Mheen, Pascal G. Doornebosch, Pieter J. Tanis, Eelco J.R. de Graaf, and on behalf of the Dutch Colorectal Audit

with TME. 8 , 9 If the pathology of the local excision specimen shows a high-risk T1 rectal cancer or if the tumor is ≥T2, the patient will have unacceptable, high recurrence rates (>15%) and possibly reduced survival without further treatment compared

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Lieke Gietelink, Michel W.J.M. Wouters, Pieter J. Tanis, Marion M. Deken, Martijn G. ten Berge, Rob A.E.M. Tollenaar, J. Han van Krieken, Mirre E. de Noo, and on behalf of the Dutch Surgical Colorectal Cancer Audit Group

pathology protocol to examine a TME specimen was introduced in the 1990s, related to the start of the Dutch TME trial. 5 Because of this standardization, 97% of patients included in this trial had a reported CRM. 2 In subsequent years, until the start of

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Emil Lou, Donna D'Souza, and Andrew C. Nelson

. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology . Genet Med 2015 ; 17 : 405 – 424 . 22