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Srinivas K. Tantravahi, and Theresa L. Werner

management of early-stage tumors and treatment failure with isolated local recurrence. In medically operable patients, total hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymph node dissection is the recommended surgery for

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Armin Shahrokni, Bella Marie Vishnevsky, Brian Jang, Saman Sarraf, Koshy Alexander, Soo Jung Kim, Robert Downey, Anoushka Afonso, and Beatriz Korc-Grodzicki

Background For many cancers, surgery remains the primary curative treatment. 1 – 3 Geriatric patients experience increased rates of surgical complications compared with younger patients, leading to decreased long-term survival and delayed recovery

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Mandy R. Sakamoto, Megan Eguchi, Christine M. Azelby, Jennifer R. Diamond, Christine M. Fisher, Virginia F. Borges, Cathy J. Bradley, and Peter Kabos

prescribing opioids in patients with cancer focus on relieving acute pain or pain associated with advanced disease. 13 – 16 A recent study of patients with cancer undergoing curative-intent surgery found that 10.4% had new persistent opioid use at 1 year

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Rodger J. Winn

References 1 Vender JR Miller J Rekito A : Effect of hemostasis and electrosurgery in the development and evolution of brain tumor surgery in the late 19 th and 20 th century . Neurosurg Focus 2005 ; 18 : 1 - 7 . 2

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Stephen B. Edge and David G. Sheldon

findings from the National Surgical Adjuvant Breast Project (protocol 6). I. Intraductal carcinoma (DCIS) . Cancer 1986 ; 57 : 197 – 208 . 12 Solin LJ Kurtz J Fourquet A . Fifteen-year results of breast-conserving surgery and definitive

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Scott M. Gilbert and Brent K. Hollenbeck

prospective long-term follow-up study . Surgery 1998 ; 123 : 573 – 578 . 21 Igaki H Tachimori Y Kato H . Improved survival for patients with upper and/or middle mediastinal lymph node metastases of squamous cell carcinoma of the lower thoracic

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Alvin R. Cabrera, Kyle C. Cuneo, James J. Vredenburgh, John H. Sampson, and John P. Kirkpatrick

bevacizumab, followed by temozolomide, bevacizumab, and irinotecan (CPT-11). Four weeks after surgery, he began radiotherapy (volumetric modulated arc therapy), receiving 50.4 Gy to the left frontoparietal region with a 9-Gy boost to the tumor bed over 6

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Alimujiang Wushou, Meng Wang, Feiluore Yibulayin, Lei Feng, Meng-meng Lu, Yuan Luo, Hui Liu, and Zhi-cheng Yang

Oncology (NCCN Guidelines) for Head and Neck Cancers, 2 surgery is the primary treatment modality for all stages of OSCC, whereas the addition of adjuvant therapeutic regimens, including radiation therapy and chemotherapy, and the use of targeted

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Jeffrey F. Moley

confirm the indolent nature of the disease and suggest the benefit of therapeutic interventions that keep tumor burden at a minimum (reoperative surgery when technically possible, cytostatic agents, selective use of external-beam radiation therapy [EBRT

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Stephanie A. Terezakis and Nancy Y. Lee

invasive cancer not presenting until 20 to 30 years of age. 10 , 11 Genetic screening should be performed for all patients presenting with MTC because surgery for early-stage disease is curative. 8 , 13 – 16 Before surgery, patients must undergo