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, 142 abemaciclib, and 91 ribociclib). Among those with baseline performance status (n=307), 268 (87%) pts had an Eastern Cooperative Oncology Group performance status of 0-1. The most common metastatic sites at index were bone (74%), visceral metastases

an urban setting ( Table 1 ). Metastases of the brain, bone and liver were noted at diagnosis for 30.3%, 50.6% and 17.4% of patients, respectively. During initial mNSCLC treatment, 41.6% of patients received radiation, and 7.4% received surgery. The

cell line, as in humans. Orthotopic implanted pancreatic cancer in hamsters could mimic the features of the disease with hepatic metastases rate of 60%.Our aim was to clarify the effectiveness of this gene therapy in hamster experimental cancer model

. Cervical metastases from an occult primary site . Semin Surg Oncol 1991 ; 7 : 2 – 8 . 5. Issing WJ Taleban B Tauber S . Diagnosis and management of carcinoma of unknown primary in the head and neck . Eur Arch Otorhinolaryngol 2003 ; 260

Metastases from Solid Malignancies Principal Investigator: John C. Grecula, MD Condition: Brain metastases from solid tumors Institution: The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute

, MD • 646-888-4162 Jedd Wolchok, MD, PhD • 646-888-2395 ClinicalTrials.gov Identifier: NCT01682213 A Phase I Trial of Vorinostat Concurrent With Stereotactic Radiotherapy in Treatment of Brain Metastases From Non–Small Cell Lung Cancer

prognosis of TNM stage II colorectal cancer . Eur J Cancer 2005 ; 41 : 272 – 279 . 18 Newland RC Dent OF Lyttle MN . Pathologic determinants of survival associated with colorectal cancer with lymph node metastases. A multivariate analysis of

favorable-histology Wilms tumor (FHWT) and pulmonary metastases limited to the lungs that fail to resolve completely after an initial 5-week period of chemotherapy with the combination of vincristine/dactinomycin/doxorubicin, based on a comparison of the

magnification ×100). PET/CT revealed right-sided lung metastases and lymph node involvement in the right axilla. Based on the large size of the tumor and axillary lymphadenopathy, the outside institution opted to excise the SC with negative margins and

. Nat Rev Cancer 2009 ; 9 : 239 – 252 . 13 Coleman RE . Skeletal complications of malignancy . Cancer 1997 ; 80 ( 8 Suppl ): 1588 – 1594 . 14 Galasko C . The anatomy and pathways of skeletal metastases . In: Weiss L Gilbert