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Al B. Benson III, Michael I. D’Angelica, Thomas A. Abrams, Chandrakanth Are, P. Mark Bloomston, Daniel T. Chang, Bryan M. Clary, Anne M. Covey, William D. Ensminger, Renuka Iyer, R. Kate Kelley, David Linehan, Mokenge P. Malafa, Steven G. Meranze, James O. Park, Timothy Pawlik, James A. Posey, Courtney Scaife, Tracey Schefter, Elin R. Sigurdson, G. Gary Tian, Jean-Nicolas Vauthey, Alan P. Venook, Yun Yen, Andrew X. Zhu, Karin G. Hoffmann, Nicole R. McMillian, and Hema Sundar

gemcitabine chemotherapy as options for adjuvant treatment. See “Adjuvant Chemotherapy and Chemoradiation for Biliary Tract Cancers,” page 1172. Management of Unresectable or Metastatic Disease Preoperative evaluation and a biopsy to confirm the

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Gregory P. Kalemkerian

thoracic surgery community, the primary additions to the literature have been retrospective reviews of institutional or registry data. That said, both Schneider et al. and the NCCN Guidelines Panel for SCLC agree that surgery followed by adjuvant

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Sherif R. Z. Abdel-Misih, Lai Wei, Al B. Benson III, Steven Cohen, Lily Lai, John Skibber, Neal Wilkinson, Martin Weiser, Deborah Schrag, and Tanios Bekaii-Saab

chemotherapy after preoperative therapy for rectal cancer. 23 This study concluded that adjuvant chemotherapy demonstrated no statistically significant improvement in disease-free survival or OS in patients after neoadjuvant treatment. This naturally prompts

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Heidi Klepin, Supriya Mohile, and Arti Hurria

– 1717 . 33 Zauderer M Patil S Hurria A . Feasibility and toxicity of dose-dense adjuvant chemotherapy in older women with breast cancer . Breast Cancer Res Treat 2008 ; in press . 34 Yancik R Wesley MN Ries LA . Effect of age

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Robert J. Downey and Lee M. Krug

. Ann Thorac Surg 1992 ; 54 : 498 – 501 . 12 Coolen L Van den Eeckhout A Deneffe G . Surgical treatment of small cell lung cancer . Eur J Cardio-Thorac Surg 1995 ; 9 : 59 – 64 . 13 Shepherd FA Evans WK Feld R . Adjuvant

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Mary F. Mulcahy, Andrew O. Wahl, and William Small Jr.

III trial of adjuvant chemotherapy with gemcitabine vs. observation in patients with resected pancreatic cancer . J Clin Oncol 2005 ; 23 ( suppl ): 1092S . 5 Tepper J Nardi G Sutt H . Carcinoma of the pancreas: review of MGH experience

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Robert J. Motzer, Eric Jonasch, Neeraj Agarwal, Clair Beard, Sam Bhayani, Graeme B. Bolger, Sam S. Chang, Toni K. Choueiri, Brian A. Costello, Ithaar H. Derweesh, Shilpa Gupta, Steven L. Hancock, Jenny J. Kim, Timothy M. Kuzel, Elaine T. Lam, Clayton Lau, Ellis G. Levine, Daniel W. Lin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Elizabeth R. Plimack, Edward N. Rampersaud, Bruce G. Redman, Charles J. Ryan, Joel Sheinfeld, Brian Shuch, Kanishka Sircar, Brad Somer, Richard B. Wilder, Mary Dwyer, and Rashmi Kumar

associated with an increased risk of cancer and heart disease. However, if adjuvant chemotherapy is chosen, the NCCN Guidelines for Testicular Cancer recommend carboplatin AUC × 7 for either 1 or 2 cycles as a category 2A recommendation for patients with

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Steven M. Grunberg

effect of a consensus statement on the practice of physicians . N Engl J Med 1989 ; 321 : 1306 – 1311 . 26 Drug Utilization Review Team in Oncology . Antiemetic prescription in Italian breast cancer patients submitted to adjuvant

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Crystal S. Denlinger, Jennifer A. Ligibel, Madhuri Are, K. Scott Baker, Wendy Demark-Wahnefried, Debra L. Friedman, Mindy Goldman, Lee Jones, Allison King, Grace H. Ku, Elizabeth Kvale, Terry S. Langbaum, Kristin Leonardi-Warren, Mary S. McCabe, Michelle Melisko, Jose G. Montoya, Kathi Mooney, Mary Ann Morgan, Javid J. Moslehi, Tracey O'Connor, Linda Overholser, Electra D. Paskett, Muhammad Raza, Karen L. Syrjala, Susan G. Urba, Mark T. Wakabayashi, Phyllis Zee, Nicole R. McMillian, and Deborah A. Freedman-Cass

-dose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial . Cancer 2004 ; 100 : 2292 – 2299 . 9. Wefel JS Lenzi R Theriault R . ‘Chemobrain’ in breast carcinoma?: a prologue . Cancer 2004

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Rodger J. Winn

. Discrepancy between consensus recommendations and actual community use of adjuvant chemotherapy in women . Ann Intern Med 2003 ; 138 : 90 – 97 . 12 Bloom BJ de Pourourville N Chhatre S . Breast cancer treatment in clinical practice compared to