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Emily C. Harrold, Ahmad F. Idris, Niamh M. Keegan, Lynda Corrigan, Min Yuen Teo, Martin O’Donnell, Sean Tee Lim, Eimear Duff, Dearbhaile M. O’Donnell, M. John Kennedy, Sue Sukor, Cliona Grant, David G. Gallagher, Sonya Collier, Tara Kingston, Ann Marie O’Dwyer, and Sinead Cuffe

findings of Palesh et al 50 among 826 patients attending oncology private practice groups in the United States, younger age and female sex represent significant risk factors for insomnia syndrome in our Irish cohort. Both these factors and cancer subtype

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Daniel G. Coit, Robert Andtbacka, Christopher K. Bichakjian, Raza A. Dilawari, Dominick DiMaio, Valerie Guild, Allan C. Halpern, F. Stephen Hodi, Mohammed Kashani-Sabet, Julie R. Lange, Anne Lind, Lainie Martin, Mary C. Martini, Scott K. Pruitt, Merrick I. Ross, Stephen F. Sener, Susan M. Swetter, Kenneth K. Tanabe, John A. Thompson, Vijay Trisal, Marshall M. Urist, Jeffrey Weber, and Michael K. Wong

: 127 – 136 . 114 Allen PJ Coit DG . The surgical management of metastatic melanoma . Ann Surg Oncol 2002 ; 9 : 762 – 770 . 115 Ferrone CR Ben Porat L Panageas KS . Clinicopathological features of and risk factors for multiple

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Robert W. Carlson, D. Craig Allred, Benjamin O. Anderson, Harold J. Burstein, W. Bradford Carter, Stephen B. Edge, John K. Erban, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Lori J. Goldstein, William J. Gradishar, Daniel F. Hayes, Clifford A. Hudis, Britt-Marie Ljung, David A. Mankoff, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Lori J. Pierce, Elizabeth C. Reed, Jasgit Sachdev, Mary Lou Smith, George Somlo, John H. Ward, Antonio C. Wolff, and Richard Zellars

of most breast cancer cases is unknown. However, numerous risk factors for the disease have been established, including female gender, increasing patient age, family history of breast cancer at a young age, early menarche, late menopause, older age at

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Robert J. Morgan Jr., Ronald D. Alvarez, Deborah K. Armstrong, Barry Boston, Robert A. Burger, Lee-may Chen, Larry Copeland, Marta Ann Crispens, David Gershenson, Heidi J. Gray, Perry W. Grigsby, Ardeshir Hakam, Laura J. Havrilesky, Carolyn Johnston, Shashikant Lele, Ursula A. Matulonis, David M. O'Malley, Richard T. Penson, Steven W. Remmenga, Paul Sabbatini, Russell J. Schilder, Julian C. Schink, Nelson Teng, and Theresa L. Werner

. The median age at diagnosis is 63 years, and 70% of patients present with advanced disease. 4 Epidemiologic studies have identified risk factors for ovarian cancer. A 30% to 60% decreased risk of cancer is associated with younger age at pregnancy and

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Benjamin M. Parsons, Dipesh Uprety, Angela L. Smith, Andrew J. Borgert, and Leah L. Dietrich

2-positive population). Our analysis supports hormone receptor status as a predictive risk factor in node-negative breast cancer <2 cm, because patients with ER/PR-negative tumors had poorer survival overall than those with ER- or PR-positivity (HR

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David S. Ettinger, Wallace Akerley, Gerold Bepler, Matthew G. Blum, Andrew Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd L. Demmy, Apar Kishor P. Ganti, Ramaswamy Govindan, Frederic W. Grannis Jr., Thierry Jahan, Mohammad Jahanzeb, David H. Johnson, Anne Kessinger, Ritsuko Komaki, Feng-Ming Kong, Mark G. Kris, Lee M. Krug, Quynh-Thu Le, Inga T. Lennes, Renato Martins, Janis O'Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, George R. Simon, Scott J. Swanson, Douglas E. Wood, and Stephen C. Yang

; symptomatic patients are more likely to have chronic obstructive pulmonary disease. The primary risk factor for lung cancer is smoking, which accounts for more than 85% of all lung cancer-related deaths. 2 The risk for lung cancer increases with the number

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Eva Battaglini, David Goldstein, Peter Grimison, Susan McCullough, Phil Mendoza-Jones, and Susanna B. Park

. Understanding the risk factors related to persistent CIPN is important to enable the design of preventive strategies. There is a current lack of effective preventive measures for CIPN. Dose modification is the only preventive strategy recommended by ASCO

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Fei Gao, Nan Li, YongMei Xu, and GuoWang Yang

all patients showed that age (≥60 years), male sex, nonadenocarcinoma pathologic type, higher T and N stages, and ≥6 positive regional lymph nodes were independent risk factors for a prognosis indicating shorter survival. Chemotherapy was a favorable

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The UNMC Eppley Cancer Center at The Nebraska Medical Center

An estimated 38,890 Americans will be diagnosed with kidney cancer and 12,840 will die of this disease in the United States in 2006. Renal cell carcinoma (RCC) constitutes approximately 2% of all malignancies, with a median age at diagnosis of 65 years. Smoking and obesity are among the risk factors for RCC development, and tumor grade, local extent of the tumor, presence of regional nodal metastases, and evidence of metastatic disease at presentation are the most important prognostic determinants of 5-year survival. These guidelines discuss evaluation, staging, treatment, and management after treatment.

For the most recent version of the guidelines, please visit NCCN.org

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In 2006, an estimated 62,190 new cases of melanoma will be diagnosed, and approximately 7910 patients will die of the disease in the United States. The incidence of melanoma continues to increase dramatically. Risk factors for melanoma include family history, dysplastic nevi, and fair skin that sunburns easily; however, melanoma can occur in any ethnic group and in people who have not had substantial sun exposure. The NCCN Melanoma guidelines attempt to distill and simplify an enormous body of knowledge and experience into fairly simple management algorithms.

For the most recent version of the guidelines, please visit NCCN.org