Search Results

You are looking at 121 - 130 of 4,071 items for :

  • Refine by Access: All x
Clear All
Full access

Ten Years of Progress Against Breast Cancer: A Partnership of Basic and Clinical/Translational Science

Robert W. Carlson and on behalf of the NCCN Breast Cancer Panel

The past 10 years have witnessed multiple important advances in the systemic treatment of breast cancer ( Table 1 ). These advances have resulted from a better understanding of the underlying biology of breast cancer, the development of new

Full access

Smoking Cessation and Pancreatic Cancer Risk in Individuals With Prediabetes and Diabetes: A Nationwide Cohort Study

Joo-Hyun Park, Jung Yong Hong, Jay J. Shen, Kyungdo Han, Young Suk Park, and Joon Oh Park

Background Pancreatic cancer is the third leading cause of cancer-related deaths in the United States, with a 5-year survival rate of 10%. 1 The incidence and mortality rates of pancreatic cancer are rapidly increasing worldwide, especially

Full access

Addressing Distress in Patients With Head and Neck Cancers: A Mental Health Quality Improvement Project

Natalie Riblet, Karen Skalla, Auden McClure, Karen Homa, Alison Luciano, and Thomas H. Davis

Symptoms of psychological distress, such as depression and anxiety, are common with any cancer but are particularly prevalent with head and neck cancers (HNCs), affecting as many as 35% of patients. 1 , 2 Several factors likely contribute to risk

Full access

Bone Cancer Guidelines

Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance

Primary bone cancers are extremely rare neoplasms, accounting for less than 0.2% of all cancers. Primary bone cancers show wide clinical heterogeneity and, perhaps most importantly, are often curable. With current multimodality treatment, including multi-agent chemotherapy, approximately three quarters of all patients diagnosed with osteosarcoma are cured. Updates for 2007 include changes in recommendations for treating chondrosarcoma, Ewing's sarcoma, and osteosarcoma.

For the most recent version of the guidelines, please visit

Full access

Testicular Cancer

Robert J. Motzer, Neeraj Agarwal, Clair Beard, Sam Bhayani, Graeme B. Bolger, Mark K. Buyyounouski, Michael A. Carducci, Sam S. Chang, Toni K. Choueiri, Shilpa Gupta, Steven L. Hancock, Gary R. Hudes, Eric Jonasch, Timothy M. Kuzel, Clayton Lau, Ellis G. Levine, Daniel W. Lin, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Thomas W. Ratliff, Bruce G. Redman, Cary N. Robertson, Charles J. Ryan, Joel Sheinfeld, Jue Wang, and Richard B. Wilder

Overview An estimated 8590 new cases of testicular cancer will be diagnosed in the United States in 2012. 1 Germ cell tumors (GCTs) constitute 95% of malignant tumors arising in the testes. These tumors also occur occasionally in extragonadal

Full access

Current Status of MRI and PET in the NCCN Guidelines for Prostate Cancer

Brandon R. Mason, James A. Eastham, Brian J. Davis, Lance A. Mynderse, Thomas J. Pugh, Richard J. Lee, and Joseph E. Ippolito

Role of Multiparametric MRI in Diagnosis Conventional screening for prostate cancer (PCa) consists of digital rectal examination (DRE) and serum prostate-specific antigen (PSA) testing, followed by transrectal ultrasound (TRUS)–guided prostate

Full access

Use and Effectiveness of Adjuvant Chemotherapy for Stage III Colon Cancer: A Population-Based Study

Christopher M. Booth, Sulaiman Nanji, Xuejiao Wei, Yingwei Peng, James J. Biagi, Timothy P. Hanna, Monika K. Krzyzanowska, and William J. Mackillop

Background International treatment guidelines have recommended 5-fluorouracil (FU)–based adjuvant chemotherapy (ACT) for patients with stage III colon cancer since the 1990s. 1 This is based on a series of randomized controlled trials (RCTs

Full access

Colorectal Cancer Screening Clinical Practice Guidelines

City of Hope Cancer Center

Colorectal cancer is the third most frequently diagnosed cancer in men and women in the United States. An estimated 104,950 new cases of colon cancer and 40,340 new cases of rectal cancer will occur in the United States in 2005. During the same year, an estimated 56,290 people will die from colon and rectal cancer. Because patients with localized colon cancer have a 90% 5-year survival rate, screening is a critical and particularly effective procedure for colorectal cancer prevention. Screening options include colonoscopy; combined fecal occult blood test (FOBT) and sigmoidoscopy; sigmoidoscopy alone; or double-contrast barium enema.

For the most recent version of the guidelines, please visit

Full access

Subdivision of M1 Stage for De Novo Metastatic Breast Cancer to Better Predict Prognosis and Response to Primary Tumor Surgery

Caijin Lin, Jiayi Wu, Shuning Ding, Chihwan Goh, Lisa Andriani, Shuangshuang Lu, Kunwei Shen, and Li Zhu

Background Approximately 5% to 10% of patients with newly diagnosed breast cancer have distant metastases, with 5-year cancer-specific mortality (CSM) ranging from 60% to 74% among different races/ethnicities. 1 Median overall survival of patients

Full access

Status of Cancer Care at Network Sites of the Nation’s Academic Cancer Centers

Stanton L. Gerson, Kate Shaw, Louis B. Harrison, Randall F. Holcombe, Laura Hutchins, Carrie B. Lee, Patrick J. Loehrer Sr, Daniel Mulkerin, W. Thomas Purcell, Lois Teston, Louis M. Weiner, and George J. Weiner

Background Cancer care in the United States is in a period of stunningly rapid yet essential transformation. The lion’s share of research progress, and the attendant improvement in patient care, occurs at the nation’s academic cancer centers