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Breast Cancer, Version 1.2016

William J. Gradishar, Benjamin O. Anderson, Ron Balassanian, Sarah L. Blair, Harold J. Burstein, Amy Cyr, Anthony D. Elias, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Matthew Goetz, Lori J. Goldstein, Clifford A. Hudis, Steven J. Isakoff, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Meena Moran, Sameer A. Patel, Lori J. Pierce, Elizabeth C. Reed, Kilian E. Salerno, Lee S. Schwartzberg, Karen Lisa Smith, Mary Lou Smith, Hatem Soliman, George Somlo, Melinda Telli, John H. Ward, Dottie A. Shead, and Rashmi Kumar

BK Yang VQ Mougalian S . Neoadjuvant chemotherapy for breast cancer increases the rate of breast conservation: results from the National Cancer Database . J Am Coll Surg 2015 ; 220 : 1063 – 1069 . 6. Liedtke C Mazouni C Hess KR

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Current Concepts in Penile Cancer

Philippe E. Spiess, Simon Horenblas, Lance C. Pagliaro, Matthew C. Biagioli, Juanita Crook, Peter E. Clark, Richard E. Greenberg, and Cesar E. Ercole

standard ILND approach should be adopted if nodal metastases are detected on frozen section. Traditionally, a standard lymphadenectomy has been offered for resectable metastatic ILNs, although recent data would support neoadjuvant chemotherapy followed by

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Pelvic Bone Sarcomas: Controversies and Treatment Options

Carol D. Morris

Biol Phys 2005 ; 61 : 492 – 498 . 10 Machak GN Tkachev SI Solovyev YN . Neoadjuvant chemotherapy and local radiotherapy for high-grade osteosarcoma of the extremities . Mayo Clin Proc 2003 ; 78 : 147 – 155 . 11 Anderson P

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Diagnosis and Management of Rectal Cancer in Patients Younger Than 50 Years: Rising Global Incidence and Unique Challenges

Daenielle Lang and Kristen K. Ciombor

RAPIDO trial, which compared neoadjuvant CRT, TME, and adjuvant chemotherapy versus short-course radiation followed by neoadjuvant chemotherapy and TME. Results demonstrated that TNT was associated with a 7% lower disease-related treatment failure rate

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Emerging Multimodality Approaches to Treat Localized Esophageal Cancer

Ronan J. Kelly

be added as one of the chemotherapy regimens to be assessed in the main study. In total, 860 patients will be randomized to 3 cycles of neoadjuvant chemotherapy plus either pembrolizumab or placebo followed by surgery, and then in the adjuvant setting

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Survival Advantage With Adjuvant Chemotherapy for Locoregionally Advanced Rectal Cancer: A Veterans Health Administration Analysis

Daphna Y. Spiegel, Matthew J. Boyer, Julian C. Hong, Christina D. Williams, Michael J. Kelley, Joseph K. Salama, and Manisha Palta

delivery of >20 total fractions. Start dates for neoadjuvant chemotherapy and radiation had to be within 30 days to ensure concurrent delivery. CRT was considered neoadjuvant if surgery occurred <180 days after radiation start. AC was defined as

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NCCN Guidelines Insights: Bone Cancer, Version 2.2017

J. Sybil Biermann, Warren Chow, Damon R. Reed, David Lucas, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, G. Thomas Budd, William T. Curry, Aarati Didwania, Nicola Fabbri, Francis J. Hornicek, Joseph B. Kuechle, Dieter Lindskog, Joel Mayerson, Sean V. McGarry, Lynn Million, Carol D. Morris, Sujana Movva, Richard J. O'Donnell, R. Lor Randall, Peter Rose, Victor M. Santana, Robert L. Satcher, Herbert Schwartz, Herrick J. Siegel, Katherine Thornton, Victor Villalobos, Mary Anne Bergman, and Jillian L. Scavone

Longhi A Ferrari S . Prognostic factors in non-metastatic Ewing's sarcoma tumor of bone: an analysis of 579 patients treated at a single institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1998 . Acta Oncol 2006 ; 45 : 469 – 475

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Active Systemic Treatment of Pancreatic Cancer

Margaret Tempero

. Tempero briefly discussed the A021101 pilot study at the University of California San Diego (NCT01821612). Patients enrolled in this single-arm phase II study received neoadjuvant chemotherapy (FOLFIRINOX) and capecitabine-based CRT followed by resection

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Ten Years of Progress in Colon Cancer Therapy

Paul F. Engstrom

patients who receive neoadjuvant chemotherapy before resection of metastatic disease and the primary colon lesion, a shortened course of postsurgical chemotherapy should be considered. The section of the NCCN Guidelines on the Continuum of Care of Advanced

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Point: Sentinel Lymph Node Biopsy Is Indicated for Patients With DCIS

Hiram S. Cody III and Kimberly J. Van Zee

cancer . J Am Coll Surg 2000 ; 191 : 593 – 599 . 8 Breslin TM Cohen L Sahin A . Sentinel lymph node biopsy is accurate after neoadjuvant chemotherapy for breast cancer . J Clin Oncol 2000 ; 18 : 3480 – 3486 . 9 Dupont EL