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Renato G. Martins, Thomas A. D’Amico, Billy W. Loo Jr, Mary Pinder-Schenck, Hossein Borghaei, Jamie E. Chaft, Apar Kishor P. Ganti, Feng-Ming (Spring) Kong, Mark G. Kris, Inga T. Lennes, and Douglas E. Wood

staging system, 2 the determination of operable stage IIIA (treated with induction therapy followed by surgery) versus inoperable stage IIIA (treated with definitive chemotherapy and radiation therapy) remains controversial. Moreover, some investigators

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Mark Bloomston, Henry Kaufman, John Winston, Mark Arnold, and Edward Martin

Brown JM Bosanquet N . Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial in the United Kingdom . Crit Rev Oncol Hematol 2000 ; 33 : 99 – 103 . 8 Kaiser AM

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Raymond Jang, Gail Darling, and Rebecca K.S. Wong

resectable esophageal cancer should receive preoperative or postoperative therapy along with surgery, how to choose between these options, and whether surgery can be avoided in candidates for both definitive chemoradiotherapy and definitive combined modality

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David S. Ettinger, Wallace Akerley, Hossein Borghaei, Andrew C. Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D’Amico, Todd L. Demmy, Apar Kishor P. Ganti, Ramaswamy Govindan, Frederic W. Grannis Jr, Leora Horn, Thierry M. Jahan, Mohammad Jahanzeb, Anne Kessinger, Ritsuko Komaki, Feng-Ming (Spring) Kong, Mark G. Kris, Lee M. Krug, Inga T. Lennes, Billy W. Loo Jr, Renato Martins, Janis O’Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Mary C. Pinder-Schenck, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, Scott J. Swanson, Douglas E. Wood, Stephen C. Yang, Miranda Hughes, and Kristina M. Gregory

therapy), thus sparing these patients from unnecessary futile treatment. If metastatic disease is discovered during surgery, then extensive surgery is often aborted. Decisions regarding treatment should be based on multidisciplinary discussion. Risk

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Kshama Jaiswal, Madelyne Hull, Anna L. Furniss, Reina Doyle, Natalia Gayou, and Elizabeth Bayliss

surgery, to chemotherapy, to radiation therapy (RT). Some studies have examined the time to diagnosis of breast cancer, whereas others have focused on time from diagnosis to surgical treatment. 2 , 4 – 8 Yet others have examined the interval from surgery

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Francisco Civantos

Dysplastic lesions of the oral cavity and larynx are extremely common and are largely being ignored, declared Francisco Civantos, MD, FACS, Co-Director of the Division of Head and Neck Surgery at the University of Miami Miller School of Medicine

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Meic H. Schmidt, Paul Klimo Jr, and Frank D. Vrionis

. The surgical treatment of metastatic disease of the spine . Radiother Oncol 2000 ; 56 : 335 – 339 . 46 Jonsson B Sjostrom L Olerud C . Outcome after limited posterior surgery for thoracic and lumbar spine metastases . Eur Spine J 1996

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Lingling Du and Andrea Wang-Gillam

have a better chance of depleting micrometastases, and it helps identify patients with aggressive tumor who are unlikely to benefit from surgery. Additionally, possible tumor shrinkage from neoadjuvant therapy may improve the R0 resection rate in

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Neil K. Taunk, Daniel E. Spratt, Mark Bilsky, and Yoshiya Yamada

. Role of RT in RCC RT has little role in treating primary localized RCC. Surgery is the primary modality for localized RCC and select metastatic cases for cytoreduction. 6 Two prospective trials examining preoperative RT showed no significant survival

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Jaffer A. Ajani, Thomas A. D’Amico, David J. Bentrem, Joseph Chao, Carlos Corvera, Prajnan Das, Crystal S. Denlinger, Peter C. Enzinger, Paul Fanta, Farhood Farjah, Hans Gerdes, Michael Gibson, Robert E. Glasgow, James A. Hayman, Steven Hochwald, Wayne L. Hofstetter, David H. Ilson, Dawn Jaroszewski, Kimberly L. Johung, Rajesh N. Keswani, Lawrence R. Kleinberg, Stephen Leong, Quan P. Ly, Kristina A. Matkowskyj, Michael McNamara, Mary F. Mulcahy, Ravi K. Paluri, Haeseong Park, Kyle A. Perry, Jose Pimiento, George A. Poultsides, Robert Roses, Vivian E. Strong, Georgia Wiesner, Christopher G. Willett, Cameron D. Wright, Nicole R. McMillian, and Lenora A. Pluchino

significant differences in outcome when comparing the same stage groups between patients receiving preoperative therapy versus those treated with surgery alone. This emphasizes the importance of having separate p and yp stage groupings to stage patients more