: anaphylaxis 15 minutes into cycle 2, a delayed reaction 1 day after completing cycle 3, and an episode of rigors, fever, tachycardia, and hypotension at completion of cycle 3. 20 The patient in the present case report received her first cycle of brentuximab
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Michael D. DeVita, Andrew M. Evens, Steven T. Rosen, Paul A. Greenberger, and Adam M. Petrich
Agda Karina Eterovic, Ossama M. Maher, Joya Chandra, Ken Chen, Jason Huse, and Wafik Zaky
treatment was stopped because disseminated fungal infection was suspected after the patient developed fever and neutropenia, and CT of the liver showed some nodularity but blood culture results were negative. Antifungal therapy was initiated for a total of 6
Van K. Morris and Cathy Eng
disease. Most patients (56%) who received all planned doses per protocol remained alive after 12 months on study. All patients experienced treatment-related AEs, most of which were infusion-related reactions, including fevers, chills, and fatigue. Given
Nathan J. Moore, Megan Othus, Anna B. Halpern, Nicholas P. Howard, Linyi Tang, Kyle E. Bastys, Mary-Elizabeth M. Percival, Paul C. Hendrie, Garrett A. Hartley, Verna L. Welch, Elihu H. Estey, and Roland B. Walter
for 1 weekly visit and when new problems arose. The physician typically saw them 1 to 2 times per cycle. All patients with neutropenic fever were admitted for intravenous antibiotics and evaluation. However, some patients were discharged to complete a
Brad Zebrack, Karen Kayser, Deborah Bybee, Lynne Padgett, Laura Sundstrom, Chad Jobin, and Julianne Oktay
psychological…social, and/or spiritual nature that may interfere with the ability to cope effectively with cancer, its physical symptoms, and its treatment.” 7 Distress is not a diagnosable disorder. Like fever or high blood pressure, distress is an indicator
Daniel E. Lage, Areej El-Jawahri, Charn-Xin Fuh, Richard A. Newcomb, Vicki A. Jackson, David P. Ryan, Joseph A. Greer, Jennifer S. Temel, and Ryan D. Nipp
.4% (n=72) had breast cancer; 31.5% (n=306) had another cancer type ( Table 1 ). Reasons for admission included symptom management (56.0%; n=544); fever or infections (24.6%; n=239); fatigue, weakness, or failure to thrive (13.5%; n=131); and metabolic
Abi Vijenthira, Lee Mozessohn, Chenthila Nagamuthu, Ning Liu, Danielle Blunt, Shabbir Alibhai, Anca Prica, and Matthew C. Cheung
spent a significantly longer number of days in the hospital compared with nonfrail patients. During both time frames, the top 3 reasons for admission among both frail and nonfrail patients were fever/infection/neutropenia, lymphoma, and symptom
Nathan J. Moore, Megan Othus, Anna B. Halpern, Nicholas P. Howard, Linyi Tang, Kyle E. Bastys, Mary-Elizabeth M. Percival, Paul C. Hendrie, Garrett A. Hartley, Verna L. Welch, Elihu H. Estey, and Roland B. Walter
for 1 weekly visit and when new problems arose. The physician typically saw them 1 to 2 times per cycle. All patients with neutropenic fever were admitted for intravenous antibiotics and evaluation. However, some patients were discharged to complete a
Ganessan Kichenadasse, John O. Miners, Arduino A. Mangoni, Andrew Rowland, Ashley M. Hopkins, and Michael J. Sorich
other cancer types or ICIs. Third, the data had investigator-reported AEs and there was no external validation/confirmation of AEs. Finally, the irAEs analyzed were organ-specific, and did not include constitutional symptoms such as fatigue and fever
Michael J. Berger, David S. Ettinger, Jonathan Aston, Sally Barbour, Jason Bergsbaken, Philip J. Bierman, Debra Brandt, Dawn E. Dolan, Georgiana Ellis, Eun Jeong Kim, Steve Kirkegaard, Dwight D. Kloth, Ruth Lagman, Dean Lim, Charles Loprinzi, Cynthia X. Ma, Victoria Maurer, Laura Boehnke Michaud, Lisle M. Nabell, Kim Noonan, Eric Roeland, Hope S. Rugo, Lee S. Schwartzberg, Bridget Scullion, John Timoney, Barbara Todaro, Susan G. Urba, Dorothy A. Shead, and Miranda Hughes
serious skin reaction (drug reaction with eosinophilia and systemic symptoms [DRESS]) (see prescribing information), but other symptoms include a fever with a rash and swollen lymph glands, or swelling in the face; patients with these symptoms should seek