baseline (CT or MRI) and then approximately every 2 cycles (or every 8 weeks [± 1 week]). After 10 months, imaging will be performed approximately every 3 cycles (or every 12 weeks [± 1 week]). Patients may remain in the study until disease progression or
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Jenna F. Borkenhagen, Daniel Eastwood, Deepak Kilari, William A. See, Jonathan D. Van Wickle, Colleen A. Lawton, and William A. Hall
biomarkers along with clinical factors, including findings on DRE. 17 Multiparametric MRI and MRI-guided prostate biopsy have become integral components of patient evaluation at many institutions. 18 , 19 Multiparametric MRI can be used to confirm low
Nisar Ahmad, Denise M. Adams, Jiang Wang, Rajan Prakash, and Nagla Abdel Karim
, but because all lesions did not fully equilibrate, a subsequent abdominal ultrasound was performed and revealed multiple hypoechoic solid lesions, believed to be inconsistent with hemangiomas. An MRI of the abdomen showed numerous liver lesions of low
Kevin Yauy, Marion Imbert-Bouteille, Virginie Bubien, Clothilde Lindet-Bourgeois, Gauthier Rathat, Helene Perrochia, Gaëtan MacGrogan, Michel Longy, Didier Bessis, Julie Tinat, Stéphanie Baert-Desurmont, Maud Blanluet, Pierre Vande Perre, Karen Baudry, Pascal Pujol, and Carole Corsini
fibroid. Pelvic MRI showed a 10-cm left adnexal mass with a polylobed aspect, associated with a cystic portion that had a mucinous borderline epithelial part. The patient's CA 125 level was 237 UI/mL and carcinoembryonic antigen level was 37.6 ng/mL. The
Monique A. de Bruin, James M. Ford, and Allison W. Kurian
participating in a clinical trial to identify novel screening approaches for these patients. This screening program consists of whole-body MRI (including dedicated brain MRI), skin examination, urine cytology annually, and comprehensive laboratory studies
Therese B. Bevers, Mark Helvie, Ermelinda Bonaccio, Kristine E. Calhoun, Mary B. Daly, William B. Farrar, Judy E. Garber, Richard Gray, Caprice C. Greenberg, Rachel Greenup, Nora M. Hansen, Randall E. Harris, Alexandra S. Heerdt, Teresa Helsten, Linda Hodgkiss, Tamarya L. Hoyt, John G. Huff, Lisa Jacobs, Constance Dobbins Lehman, Barbara Monsees, Bethany L. Niell, Catherine C. Parker, Mark Pearlman, Liane Philpotts, Laura B. Shepardson, Mary Lou Smith, Matthew Stein, Lusine Tumyan, Cheryl Williams, Mary Anne Bergman, and Rashmi Kumar
imaging may include diagnostic mammography, ultrasonography, and at times diagnostic breast MRI. The eventual decision regarding need for tissue sampling is based on level of suspicion on imaging and/or clinical examination. Biopsy is needed in situations
Margaret von Mehren, R. Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Kristen N. Ganjoo, Suzanne George, Ricardo J. Gonzalez, Martin J. Heslin, John M. Kane III, Vicki Keedy, Edward Kim, Henry Koon, Joel Mayerson, Martin McCarter, Sean V. McGarry, Christian Meyer, Zachary S. Morris, Richard J. O'Donnell, Alberto S. Pappo, I. Benjamin Paz, Ivy A. Petersen, John D. Pfeifer, Richard F. Riedel, Bernice Ruo, Scott Schuetze, William D. Tap, Jeffrey D. Wayne, Mary Anne Bergman, and Jillian L. Scavone
details about tumor size and contiguity to nearby visceral structures and neurovascular landmarks. The panel recommends MRI with contrast, with or without CT with contrast. Other imaging studies such as CT angiogram and plain radiograph may be warranted in
William J. Gradishar, Benjamin O. Anderson, Ron Balassanian, Sarah L. Blair, Harold J. Burstein, Amy Cyr, Anthony D. Elias, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Matthew Goetz, Lori J. Goldstein, Clifford A. Hudis, Steven J. Isakoff, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Meena Moran, Sameer A. Patel, Lori J. Pierce, Elizabeth C. Reed, Kilian E. Salerno, Lee S. Schwartzberg, Karen Lisa Smith, Mary Lou Smith, Hatem Soliman, George Somlo, Melinda Telli, John H. Ward, Dorothy A. Shead, and Rashmi Kumar
asymptomatic early-stage breast cancer. 10 In addition, monitoring of disease relapse with any tumor markers is not recommended. Use of MRI is optional and not universally recommended by experts in the field. Breast MRI advocates note its high sensitivity
Parijatham S. Thomas
months. Screening with breast MRI was previously recommended for women with elevated risk for breast cancer predominately due to family history of breast cancer, but did not include those with history of AH or LCIS. 38 Due to insufficient evidence to
David D. Buethe and Julio Pow-Sang
Reclassification Parameters Endorectal Multiparametric MRI Recently, a single-armed prospective trial 60 examined the efficacy of multiparametric T2-weighted endorectal MRI of the prostate with and without intravenous contrast. The accuracy of the
