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Michael D. Green and James A. Hayman

disease extent. Localized Disease Management Surgery represents the primary treatment modality for the diagnosis and treatment of localized MCC in medically and technically operable patients. 9 A National Cancer Database (NCDB) study examining US

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Harry T. Whelan

) in particular have a generally poor prognosis, and surgery is rarely curative. The use of PDT for brain tumors such as HGGs and glioblastoma multiforme (GBM) moves away from the more traditional resection and systemic chemotherapy methods. With

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Ahmed Abdalla, Amr Aref, Amer Alame, Mohamad Barawi, Danny Ma, and Zyad Kafri

chemotherapy prior to conventional preoperative chemoradiation (CRT) and surgery allowed patients to receive more of their planned treatment with a better toxicity profile and increase in pathological response. However, those studies used a long course of

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Heidi J. Gray

. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix . J Clin Oncol 2000 ; 18 : 1606 – 1613 . 13. Whitney CW

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Renato G. Martins, Thomas A. D’Amico, Billy W. Loo Jr, Mary Pinder-Schenck, Hossein Borghaei, Jamie E. Chaft, Apar Kishor P. Ganti, Feng-Ming (Spring) Kong, Mark G. Kris, Inga T. Lennes, and Douglas E. Wood

staging system, 2 the determination of operable stage IIIA (treated with induction therapy followed by surgery) versus inoperable stage IIIA (treated with definitive chemotherapy and radiation therapy) remains controversial. Moreover, some investigators

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Raymond Jang, Gail Darling, and Rebecca K.S. Wong

resectable esophageal cancer should receive preoperative or postoperative therapy along with surgery, how to choose between these options, and whether surgery can be avoided in candidates for both definitive chemoradiotherapy and definitive combined modality

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Mark Bloomston, Henry Kaufman, John Winston, Mark Arnold, and Edward Martin

Brown JM Bosanquet N . Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial in the United Kingdom . Crit Rev Oncol Hematol 2000 ; 33 : 99 – 103 . 8 Kaiser AM

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David S. Ettinger, Wallace Akerley, Hossein Borghaei, Andrew C. Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D’Amico, Todd L. Demmy, Apar Kishor P. Ganti, Ramaswamy Govindan, Frederic W. Grannis Jr, Leora Horn, Thierry M. Jahan, Mohammad Jahanzeb, Anne Kessinger, Ritsuko Komaki, Feng-Ming (Spring) Kong, Mark G. Kris, Lee M. Krug, Inga T. Lennes, Billy W. Loo Jr, Renato Martins, Janis O’Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Mary C. Pinder-Schenck, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, Scott J. Swanson, Douglas E. Wood, Stephen C. Yang, Miranda Hughes, and Kristina M. Gregory

therapy), thus sparing these patients from unnecessary futile treatment. If metastatic disease is discovered during surgery, then extensive surgery is often aborted. Decisions regarding treatment should be based on multidisciplinary discussion. Risk

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Kshama Jaiswal, Madelyne Hull, Anna L. Furniss, Reina Doyle, Natalia Gayou, and Elizabeth Bayliss

surgery, to chemotherapy, to radiation therapy (RT). Some studies have examined the time to diagnosis of breast cancer, whereas others have focused on time from diagnosis to surgical treatment. 2 , 4 – 8 Yet others have examined the interval from surgery

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Meic H. Schmidt, Paul Klimo Jr, and Frank D. Vrionis

. The surgical treatment of metastatic disease of the spine . Radiother Oncol 2000 ; 56 : 335 – 339 . 46 Jonsson B Sjostrom L Olerud C . Outcome after limited posterior surgery for thoracic and lumbar spine metastases . Eur Spine J 1996