with locally advanced rectal cancer (LARC) in the United States using data from the National Cancer Database (NCDB). 8 Patients who received concurrent chemoradiation therapy without surgery had lower survival rates. 8 Others, however, used
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Helmneh M. Sineshaw, K. Robin Yabroff, V. Liana Tsikitis, Ahmedin Jemal, and Timur Mitin
Kilian E. Salerno
Cancer Panel. Adjuvant RT After Breast-Conserving Surgery In short, the NCCN recommendations for RT of invasive breast cancer after breast-conserving surgery include RT to the whole breast, with or without a boost; APBI in select patients; and
Michael D. Green and James A. Hayman
disease extent. Localized Disease Management Surgery represents the primary treatment modality for the diagnosis and treatment of localized MCC in medically and technically operable patients. 9 A National Cancer Database (NCDB) study examining US
Harry T. Whelan
) in particular have a generally poor prognosis, and surgery is rarely curative. The use of PDT for brain tumors such as HGGs and glioblastoma multiforme (GBM) moves away from the more traditional resection and systemic chemotherapy methods. With
Ahmed Abdalla, Amr Aref, Amer Alame, Mohamad Barawi, Danny Ma, and Zyad Kafri
chemotherapy prior to conventional preoperative chemoradiation (CRT) and surgery allowed patients to receive more of their planned treatment with a better toxicity profile and increase in pathological response. However, those studies used a long course of
Heidi J. Gray
. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix . J Clin Oncol 2000 ; 18 : 1606 – 1613 . 13. Whitney CW
Renato G. Martins, Thomas A. D’Amico, Billy W. Loo Jr, Mary Pinder-Schenck, Hossein Borghaei, Jamie E. Chaft, Apar Kishor P. Ganti, Feng-Ming (Spring) Kong, Mark G. Kris, Inga T. Lennes, and Douglas E. Wood
staging system, 2 the determination of operable stage IIIA (treated with induction therapy followed by surgery) versus inoperable stage IIIA (treated with definitive chemotherapy and radiation therapy) remains controversial. Moreover, some investigators
Raymond Jang, Gail Darling, and Rebecca K.S. Wong
resectable esophageal cancer should receive preoperative or postoperative therapy along with surgery, how to choose between these options, and whether surgery can be avoided in candidates for both definitive chemoradiotherapy and definitive combined modality
Mark Bloomston, Henry Kaufman, John Winston, Mark Arnold, and Edward Martin
Brown JM Bosanquet N . Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial in the United Kingdom . Crit Rev Oncol Hematol 2000 ; 33 : 99 – 103 . 8 Kaiser AM
David S. Ettinger, Wallace Akerley, Hossein Borghaei, Andrew C. Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D’Amico, Todd L. Demmy, Apar Kishor P. Ganti, Ramaswamy Govindan, Frederic W. Grannis Jr, Leora Horn, Thierry M. Jahan, Mohammad Jahanzeb, Anne Kessinger, Ritsuko Komaki, Feng-Ming (Spring) Kong, Mark G. Kris, Lee M. Krug, Inga T. Lennes, Billy W. Loo Jr, Renato Martins, Janis O’Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Mary C. Pinder-Schenck, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, Scott J. Swanson, Douglas E. Wood, Stephen C. Yang, Miranda Hughes, and Kristina M. Gregory
therapy), thus sparing these patients from unnecessary futile treatment. If metastatic disease is discovered during surgery, then extensive surgery is often aborted. Decisions regarding treatment should be based on multidisciplinary discussion. Risk
