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who undergo a complete resection of node-positive stage III tumors, adjuvant FOLFOX achieves an estimated one-third reduction in the risk of recurrence compared with surgery alone. 9 The existing evidence for the role of adjuvant therapy is largely

excision, separate groin incision, lymphatic mapping, radiation, chemotherapy, and exenteration. Surgery The goal of primary surgery is to obtain an adequate negative margin of 1 to 2 cm, Dr. Greer told the audience. Early-stage tumors (T1, smaller T2

) 79-47-51 randomized 204 patients with locally advanced rectal cancer treated with surgery to either postoperative radiation to 50.4 Gy or the same radiation regimen with concurrent bolus 5-FU with semustine both preceded and followed by adjuvant 5-FU

with locally advanced rectal cancer (LARC) in the United States using data from the National Cancer Database (NCDB). 8 Patients who received concurrent chemoradiation therapy without surgery had lower survival rates. 8 Others, however, used

Cancer Panel. Adjuvant RT After Breast-Conserving Surgery In short, the NCCN recommendations for RT of invasive breast cancer after breast-conserving surgery include RT to the whole breast, with or without a boost; APBI in select patients; and

disease extent. Localized Disease Management Surgery represents the primary treatment modality for the diagnosis and treatment of localized MCC in medically and technically operable patients. 9 A National Cancer Database (NCDB) study examining US

) in particular have a generally poor prognosis, and surgery is rarely curative. The use of PDT for brain tumors such as HGGs and glioblastoma multiforme (GBM) moves away from the more traditional resection and systemic chemotherapy methods. With

chemotherapy prior to conventional preoperative chemoradiation (CRT) and surgery allowed patients to receive more of their planned treatment with a better toxicity profile and increase in pathological response. However, those studies used a long course of

. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix . J Clin Oncol 2000 ; 18 : 1606 – 1613 . 13. Whitney CW

staging system, 2 the determination of operable stage IIIA (treated with induction therapy followed by surgery) versus inoperable stage IIIA (treated with definitive chemotherapy and radiation therapy) remains controversial. Moreover, some investigators