brachytherapy) presented with rectal bleeding. His workup, including colonoscopy, revealed 2 large masses in the rectum with central ulceration. Pathology was significant for moderately to poorly differentiated invasive adenocarcinoma with loss of MSH2 and MSH6
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Rahel Demisse, Neha Damle, Edward Kim, Jun Gong, Marwan Fakih, Cathy Eng, Leslie Oesterich, Madison McKenny, Jingran Ji, James Liu, Ryan Louie, Kit Tam, Sepideh Gholami, Wissam Halabi, Arta Monjazeb, Farshid Dayyani, and May Cho
Nathan J. Moore, Megan Othus, Anna B. Halpern, Nicholas P. Howard, Linyi Tang, Kyle E. Bastys, Mary-Elizabeth M. Percival, Paul C. Hendrie, Garrett A. Hartley, Verna L. Welch, Elihu H. Estey, and Roland B. Walter
typing; (4) laboratory charges, including all non–transfusion-related laboratory studies such as blood counts, basic metabolic panels, and lung function tests; microbiology including blood, sputum, and urine cultures; and pathology including tissue
Nikolaos A. Trikalinos, Amy Zhou, Maria B. Majella Doyle, Kathryn J. Fowler, Ashley Morton, Neeta Vachharajani, Manik Amin, Jesse W. Keller, William C. Chapman, Elizabeth M. Brunt, and Benjamin R. Tan
–approved Washington University Liver Cancer Registry. The registry has a retrospective and prospective component and collects information on consenting patients with various liver pathologies. We identified 123 patients with histopathologically proven cHCC-CCA in the
Kamel Izeradjene and Sunil R. Hingorani
Cancer Res 2000 ; 6 : 2969 – 2972 . 7. Hruban RH Iacobuzio-Donahue C Wilentz RE . Molecular pathology of pancreatic cancer . Cancer J 2001 ; 7 : 251 – 258 . 8. Kahn S Yamamoto F Almoguera C . The c-K-ras gene and human cancer
Karisa C. Schreck, Andrew Guajardo, Doris D.M. Lin, Charles G. Eberhart, and Stuart A. Grossman
presented with focal seizures and a left temporal lobe mass in 1998, which was observed until 2002 when he underwent surgery, and pathology results showed PXA. He underwent a second surgery in 2004 after demonstrating progression, with pathology still
Stephanie Alimena, Suvidya Lakshmi Pachigolla, Sarah Feldman, David Yang, Peter F. Orio III, Larissa Lee, and Martin King
disparities were further assessed by determining rates of adverse pathology (eg, positive margins or pathologic nodal involvement) among Black and non-Black women who received surgery to determine if rates of postoperative RT differed by race. Completion of RT
Venkata Pokuri, Norbert Sule, Yousef Soofi, Bo Xu, Khurshid Guru, and Saby George
transurethral resection (TUR) of the bladder tumor. After resection, the tumor base was cauterized and a mitomycin cocktail was left indwelling. Hematuria subsided with TUR. Based on pathology report, patient was started on neoadjuvant chemotherapy with a GC
Agata A. Bielska, Walid K. Chatila, Henry Walch, Nikolaus Schultz, Zsofia K. Stadler, Jinru Shia, Diane Reidy-Lagunes, and Rona Yaeger
colon masses. At total colectomy, the most advanced lesion was stage IIB. Pathology was notable for tumor-infiltrating lymphocytes (TILs) and the absence of MLH1 and PMS2 staining on immunohistochemistry ( Figure 1A ). Germline genetic testing revealed a
Benjamin O. Anderson, Kristine E. Calhoun, and Eric L. Rosen
mucin-secreting carcinoma . J Clin Pathol 1975 ; 28 : 711 – 716 . 22. Rosen P . Lobular carcinoma and hyperplasia . In: Rosen P, ed. Breast Pathology . Philadelphia : Lippincott-Raven ; 1997 : 507 – 544 . 23. Acs G Lawton
Ashley E. Ross
E. Ross, MD, PhD, of The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Dr. Ross, Assistant Professor of Urology, Oncology, and Pathology, reviewed the evidence supporting the validity of currently available molecular prognostic tests
