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E. Ross, MD, PhD, of The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Dr. Ross, Assistant Professor of Urology, Oncology, and Pathology, reviewed the evidence supporting the validity of currently available molecular prognostic tests

generated and how to use them will be the most important aspect in getting the most out of genomic testing in treating your patients,” Jennifer J.D. Morrissette, PhD, Associate Professor, Department of Clinical Pathology and Laboratory Medicine, and

colon masses. At total colectomy, the most advanced lesion was stage IIB. Pathology was notable for tumor-infiltrating lymphocytes (TILs) and the absence of MLH1 and PMS2 staining on immunohistochemistry ( Figure 1A ). Germline genetic testing revealed a

guidelines, at www.NCCN.org [ST-1]). 5 , 6 This revision differs from the 1997 edition of the AJCC staging by incorporating the increasing use of novel imaging and pathology techniques used at diagnosis (e.g., sentinel node biopsy and immunohistochemistry

Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology [published online ahead of print February 6, 2017] . J Clin Oncol , doi: 10.1200/JCO.2016.71.9807 . 2

C, and HIV. In LMCs, late-stage presentation and inaccessible diagnosis and treatment are common. Only 26% of LMCs have available pathology service, and fewer than one-third have treatment services available in the public sector. Other barriers to

subsequently underwent a dilation and curettage. Pathology results suggested leiomyosarcoma. A CT scan of the chest, abdomen, and pelvis revealed a right uterine body peripherally enhancing partially calcified necrotic 5.8 × 5.0-cm mass, bilateral pulmonary

(45 U/L). Fiberoptic bronchoscopy was performed with fine-needle aspiration (FNA) of a station 7 lymph node, and the pathology was read as poorly differentiated squamous cell carcinoma (SCC) ( Figure 2 ). Immunostains were positive for p63 and negative

, we performed a Web-based survey among pathologists at the Institute of Pathology of the Charité Medical University Berlin. In the survey, we presented the clinical information of a 54-year-old female patient with abdominal pain and the cytological

presence of bowel perforation or obstruction, specific systemic chemotherapy and targeted therapy agents, molecular pathology testing ( KRAS , BRAF , and microsatellite instability [MSI]), comorbidities, and hospital characteristics. Given the complex