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Rishi Jain, Michelle J. Savage, Andrea D. Forman, Reetu Mukherji, and Michael J. Hall

mutations and the risk of papillary thyroid cancer . Int J Cancer 2015 ; 137 : 548 – 552 . 52. Friedrichsen DM Malone KE Doody DR . Frequency of CHEK2 mutations in a population based, case-control study of breast cancer in young women

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Al B. Benson III, Thomas A. Abrams, Edgar Ben-Josef, P. Mark Bloomston, Jean F. Botha, Bryan M. Clary, Anne Covey, Steven A. Curley, Michael I. D'Angelica, Rene Davila, William D. Ensminger, John F. Gibbs, Daniel Laheru, Mokenge P. Malafa, Jorge Marrero, Steven G. Meranze, Sean J. Mulvihill, James O. Park, James A. Posey, Jasgit Sachdev, Riad Salem, Elin R. Sigurdson, Constantinos Sofocleous, Jean-Nicolas Vauthey, Alan P. Venook, Laura Williams Goff, Yun Yen, and Andrew X. Zhu

. 174 Yeh CN Jan YY Yeh TS . Hepatic resection of the intraductal papillary type of peripheral cholangiocarcinoma . Ann Surg Oncol 2004 ; 11 : 606 – 611 . 175 Nakagohri T Asano T Kinoshita H . Aggressive surgical resection for hilar

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David S. Ettinger, Mark Agulnik, Justin M. M. Cates, Mihaela Cristea, Crystal S. Denlinger, Keith D. Eaton, Panagiotis M. Fidias, David Gierada, Jon P. Gockerman, Charles R. Handorf, Renuka Iyer, Renato Lenzi, John Phay, Asif Rashid, Leonard Saltz, Lawrence N. Shulman, Jeffrey B. Smerage, Gauri R. Varadhachary, Jonathan S. Zager, and Weining (Ken) Zhen

signs. 3 , 21 - 23 Favorable prognostic factors include poorly differentiated carcinoma with midline distribution, women with papillary adenocarcinoma of the peritoneal cavity, women with adenocarcinoma involving only axillary lymph nodes, SCC involving

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Mary B. Daly, Jennifer E. Axilbund, Saundra Buys, Beth Crawford, Carolyn D. Farrell, Susan Friedman, Judy E. Garber, Salil Goorha, Stephen B. Gruber, Heather Hampel, Virginia Kaklamani, Wendy Kohlmann, Allison Kurian, Jennifer Litton, P. Kelly Marcom, Robert Nussbaum, Kenneth Offit, Tuya Pal, Boris Pasche, Robert Pilarski, Gwen Reiser, Kristen Mahoney Shannon, Jeffrey R. Smith, Elizabeth Swisher, and Jeffrey N. Weitzel

approximately 70% of individuals with Cowden syndrome, 96 and the lifetime risk for thyroid cancer (follicular or papillary) has been estimated at 3% to 10%. 11 , 97 As in many other hereditary cancer syndromes, affected individuals are more likely to develop

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Dawn Provenzale, Samir Gupta, Dennis J. Ahnen, Travis Bray, Jamie A. Cannon, Gregory Cooper, Donald S. David, Dayna S. Early, Deborah Erwin, James M. Ford, Francis M. Giardiello, William Grady, Amy L. Halverson, Stanley R. Hamilton, Heather Hampel, Mohammad K. Ismail, Jason B. Klapman, David W. Larson, Audrey J. Lazenby, Patrick M. Lynch, Robert J. Mayer, Reid M. Ness, Scott E. Regenbogen, Niloy Jewel Samadder, Moshe Shike, Gideon Steinbach, David Weinberg, Mary Dwyer, and Susan Darlow

-morular variant of papillary thyroid cancer, hepatoblastoma, or multiple gastrointestinal hamartomatous polyps). Detailed strategies for screening for Lynch syndrome are provided below; see the NCCN guidelines for detail on follow-up patients meeting risk criteria

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Kamran Aghayev, Frank Vrionis, and Marc C. Chamberlain

invasive tumors with nerve root encasement and even extravertebral invasion have been reported. Histologically, myxopapillary ependymomas are characterized by myxoid changes in the stroma and papillary organization of tumor cells. 85 Microsurgery plays an

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Mary B. Daly, Robert Pilarski, Matthew B. Yurgelun, Michael P. Berry, Saundra S. Buys, Patricia Dickson, Susan M. Domchek, Ahmed Elkhanany, Susan Friedman, Judy E. Garber, Michael Goggins, Mollie L. Hutton, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison W. Kurian, Christine Laronga, Jennifer K. Litton, Julie S. Mak, Carolyn S. Menendez, Sofia D. Merajver, Barbara S. Norquist, Kenneth Offit, Tuya Pal, Holly J. Pederson, Gwen Reiser, Kristen Mahoney Shannon, Kala Visvanathan, Jeffrey N. Weitzel, Myra J. Wick, Kari B. Wisinski, Mary A. Dwyer, and Susan D. Darlow

, although long-term studies are needed in this area. Lesions detected through routine screening may not always require resection (eg, sporadic branch duct intraductal papillary mucinous neoplasms). Therefore, larger long-term studies are needed to further

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, endometrial, papillary urothelial, gastric, melanoma, and urinary tract cancers. More research is needed to understand the relationship between PALB2 and other cancer risks, particularly in males because they represented <1% of patients tested in this study

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%) malignant fibrous histiocytoma, 2 (<1%) papillary cystadenocarcinoma, 2 (<1%) Merkel cell carcinoma, 2 (<1%), myoepithelial carcinoma, 2 (<1%) malignant mixed tumor, 1 (<1%)adenocarcinoma, and 15 (5%) unknown carcinoma. Tumor grade was also studied: 35 (13

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Alan P. Venook, Maria E. Arcila, Al B. Benson III, Donald A. Berry, David Ross Camidge, Robert W. Carlson, Toni K. Choueiri, Valerie Guild, Gregory P. Kalemkerian, Razelle Kurzrock, Christine M. Lovly, Amy E. McKee, Robert J. Morgan, Anthony J. Olszanski, Mary W. Redman, Vered Stearns, Joan McClure, and Marian L. Birkeland

, constitute many different histologies, including type I and type II papillary and chromophobe tumors. Among the clear cell subset, 2 groups of molecularly targeted therapies have emerged for the treatment of metastatic disease; 5 agents target the VEGF