marrow, and gastrointestinal tract); the remaining patients presented with both nodal and extranodal disease. 8 Systemic symptoms (fever, night sweats, weight loss, and fatigue) were uncommon and mostly occurred in patients with both nodal and extranodal
Search Results
Interdigitating Dendritic Cell Sarcoma
Venkata K. Pokuri, Mihai Merzianu, Shipra Gandhi, Junaid Baqai, Thom R. Loree, and Seema Bhat
Metastatic Insulinoma: Current Molecular and Cytotoxic Therapeutic Approaches for Metastatic Well-Differentiated panNETs
Iulia Giuroiu and Diane Reidy-Lagunes
important to minimize treatment-related adverse effects, which can include pain, nausea, fever, fatigue, and liver abnormalities. Systemic Cytotoxic Therapy Treatment No clearly defined role currently exists for conventional chemotherapy in the
Targeting BRAF Mutations in High-Grade Neuroendocrine Carcinoma of the Colon
Jarred Burkart, Dwight Owen, Manisha H. Shah, Sherif R. Z. Abdel-Misih, Sameek Roychowdhury, Robert Wesolowski, Sigurdis Haraldsdottir, Julie W. Reeser, Eric Samorodnitsky, Amy Smith, and Bhavana Konda
onset abdominal pain and fevers, and imaging results were concerning for abscess formation at the anastomotic site. He underwent exploratory laparotomy, ileocolostomy resection, and abdominal washout with wide drainage for ileocolostomy perforation
Donor-Derived T-Cell Large Granular Lymphocytic Leukemia in a Patient With Peripheral T-Cell Lymphoma
Juliana E. Hidalgo Lopez, Mariko Yabe, Adrian A. Carballo-Zarate, Sa A. Wang, Jeffrey L. Jorgensen, Sairah Ahmed, John Lee, Shaoying Li, Ellen Schlette, Timothy McDonnell, Roberto N. Miranda, L. Jeffrey Medeiros, Carlos E. Bueso-Ramos, and C. Cameron Yin
-LGL leukemia and T-LGL proliferation and other lymphoproliferative disorders after SCT is proposed. Case Report A 16-year-old man initially presented to another hospital with fever, weight loss, lymphadenopathy, and hepatosplenomegaly in October 2012. A
KRAS G12V Mutation in Acquired Resistance to Combined BRAF and MEK Inhibition in Papillary Thyroid Cancer
Dwight H. Owen, Bhavana Konda, Jennifer Sipos, Tom Liu, Amy Webb, Matthew D. Ringel, Cynthia D. Timmers, and Manisha H. Shah
to a nadir of 385 ng/mL at the time of disease progression. The patient’s treatment course was complicated by rash and fevers, which required low doses of prednisone and reduced doses of dabrafenib (100 mg orally twice daily) and trametinib (1.5 mg
Successful Use of BRAF/MEK Inhibitors as a Neoadjuvant Approach in the Definitive Treatment of Papillary Craniopharyngioma
Karam Khaddour, Michael R. Chicoine, Jiayi Huang, Sonika Dahiya, and George Ansstas
reduction. The treatment course with trametinib and dabrafenib continued for a total of 9 months. The patient experienced mild pyrexia (grade I fever according to CTCAE version 5.0.), which required treatment interruption for 4 days before later resuming the
A 66-Year-Old Woman With Newly Diagnosed Oligometastatic Non–Small Cell Lung Cancer
Stacey Shiovitz and Keith D. Eaton
Case Report A 66-year-old woman presented with newly diagnosed stage IV non–small cell lung cancer (NSCLC) and a large adrenal metastasis. Five weeks before presentation, she developed low-grade fevers and shortness of breath with minimal
Cutaneous T-Cell Lymphoma in Sub-Saharan Africa
Matthew Ulrickson, Fred Okuku, Victoria Walusansa, Oliver Press, Sam Kalungi, David Wu, Fred Kambugu, Corey Casper, and Jackson Orem
Mulago Hospital reporting a 7-year history of gradually increasing pruritus and diffuse, scaly skin lesions ( Figure 1A ). More recently he reported mild weight loss and anorexia, although he denied having drenching night-sweats or fevers. He denied any
A Case of Diffuse Large B-Cell Lymphoma in Association With Paraesophageal Leiomyoma: Highlighting False-Positivity of PET Scan and Importance of Tissue Diagnosis
Rajinder S. Grover, Kemp Kernstine, and Amrita Krishnan
56-year-old woman noted a slowly enlarging right parotid mass for approximately 2 months. She denied any fever, night sweats, decreased salivation, dry eyes, pain, or facial paresthesias. She had an intentional weight loss of about 19 pounds over the
Full Spectrum: Efficacy and Toxicity of Immunotherapy in Metastatic Melanoma
Matthew Zibelman and Anthony J. Olszanski
, dysphagia, or dyspnea. He reported no significant weight loss, fevers, or chills, and had not noticed any other masses or unusual skin lesions. He did report mild fatigue. A brief trial of antibiotics was prescribed by a primary care physician but did not