%, and all G neuropathy from 5% to 39%, if OS increased by 17, 4, and 2 months, respectively. In addition, pts would require an increase in OS of 1 month to accept an increase in G3/4 fatigue from 1% to 12% or all G pneumonitis from <1% to 8%. Preferences
Search Results
HSR20-106: Quantifying Patient Preferences for Attributes Associated With First-Line Treatment of Metastatic Non-Small Cell Lung Cancer
Brian Seal, Candice Yong, M. Janelle Cambron-Mellott, Oliver Will, Martine C. Maculaitis, Kelly Clapp, Emily Mulvihill, Ion Cotarla, and Ranee Mehra
Communicating About Chemotherapy-Induced Nausea and Vomiting: A Comparison of Patient and Provider Perspectives
John M. Salsman, Steven M. Grunberg, Jennifer L. Beaumont, Miriam Rogers, Diane Paul, Marla L. Clayman, and David Cella
, available online, in this article, at www.JNCCN.org ) Nausea and Vomiting Management Barriers Questionnaire (NVMBQ) were developed using the Fatigue Management Barriers Questionnaire (FMBQ) 16 as a template. Patient-related barriers to communicating about
Role of Adjuvant and Posttreatment Exercise Programs in Breast Health
Jennifer A. Ligibel
diagnosis have lower rates of recurrence and death compared with sedentary individuals. A growing number of exercise intervention studies show that increased physical activity after diagnosis leads to improvements in quality of life, fatigue, and body image
Urothelial Carcinoma of the Bladder and the Rise of Immunotherapy
David D. Chism
-related AEs (TRAEs) included fatigue, pneumonitis, rash, and dyspnea. Among the 119 cisplatin-ineligible patients in cohort 1 who received atezolizumab in the first-line setting, there was an ORR of 23% (95% CI, 16–31) and a CR of 9%, with durable responses
Distress Screening and the Integration of Psychosocial Care Into Routine Oncologic Care
Jimmie C. Holland
-report was considered totally invalid,” explained Dr. Holland. To begin to measure subjective symptoms, validated, quantitative tools were developed in the 1970s and 1980s. Scales focused on items such as health-related quality of life, pain, fatigue
Targeting Angiogenesis in Advanced Non-Small Cell Lung Cancer
Philip E. Lammers and Leora Horn
show superiority. The toxicities differed between arms; more grade 3/4 thrombocytopenia (23.3% vs 5.6%), anemia (14.5% vs 2.7%), and fatigue (10.9% vs 5.0%) were seen in the pemetrexed group, whereas more grade 3/4 neutropenia (40.6% vs 25.8%), febrile
The NCCN 2023 Annual Conference
and suggested approaches that can improve inclusion and equity in oncology. In another plenary session focused on sleep disorders, fatigue, and cognitive function in cancer survivors (synopsis available at JNCCN.org ) speakers again noted the need
New Meets Old: A Case Study and Review of Novel Therapeutics for the Treatment of CLL in Older Patients
Neel K. Gupta and Charalambos Andreadis
performed. He was asymptomatic, without palpable adenopathy or organomegaly, and was monitored expectantly during the next 5 years, remaining free of symptoms or hematologic abnormalities. By August 2009 he developed mild fatigue, cervical lymphadenopathy
Prevalence of Insomnia in an Oncology Patient Population: An Irish Tertiary Referral Center Experience
Emily C. Harrold, Ahmad F. Idris, Niamh M. Keegan, Lynda Corrigan, Min Yuen Teo, Martin O’Donnell, Sean Tee Lim, Eimear Duff, Dearbhaile M. O’Donnell, M. John Kennedy, Sue Sukor, Cliona Grant, David G. Gallagher, Sonya Collier, Tara Kingston, Ann Marie O’Dwyer, and Sinead Cuffe
trajectory, with an impact on multiple functional domains and a deleterious effect on overall quality of life. 48 Improving sleep outcomes is significantly related to improvements in quality of life and reduced daytime fatigue. 49 Data also suggest an
Systematic Review of Randomized Controlled Trials of Exercise Interventions Using Digital Activity Trackers in Patients With Cancer
Kerry Schaffer, Narmadha Panneerselvam, Kah Poh Loh, Rachel Herrmann, Ian R. Kleckner, Richard Francis Dunne, Po-Ju Lin, Charles E. Heckler, Nicholas Gerbino, Lauren B. Bruckner, Eugene Storozynsky, Bonnie Ky, Andrea Baran, Supriya Gupta Mohile, Karen Michelle Mustian, and Chunkit Fung
intensity as part of routine cancer care. Poor adherence to exercise interventions is a major barrier to achieving the optimal benefits of exercise. 13 – 16 The presence of symptoms related to cancer and its treatments, including fatigue, depression