chemotherapy and TRT. Other studies have investigated the role of surgical resection for newly diagnosed LS-SCLC followed by adjuvant chemotherapy. The Japan Clinical Oncology Lung Cancer Study Group evaluated 61 patients with LS-SCLC from 17 centers: 44 had
Search Results
Bryan J. Schneider, Ashish Saxena, and Robert J. Downey
Margaret Tempero
study by Neoptolemos et al, 3 adjuvant chemotherapy was linked to a significant surgical benefit in this setting, but adjuvant CRT had a “deleterious effect” on survival. “CRT after resection was not a good thing,” she added. However, Dr. Tempero noted
Robert W. Carlson, Elizabeth Brown, Harold J. Burstein, William J. Gradishar, Clifford A. Hudis, Charles Loprinzi, Eleftherios Paul Mamounas, Edith A. Perez, Kathleen Pritchard, Peter Ravdin, Abram Recht, George Somlo, Richard L. Theriault, Eric P. Winer, Antonio C. Wolff, and for the NCCN Adjuvant Therapy for Breast Cancer Task Force
predictive factors? Can certain subsets of premenopausal women with ER-positive tumors be adequately treated using tamoxifen and/or ovarian suppression and forego adjuvant chemotherapy? What is the optimal strategy for using aromatase inhibitors (AIs) in the
Margaret von Mehren, John M. Kane, Mark Agulnik, Marilyn M. Bui, Janai Carr-Ascher, Edwin Choy, Mary Connelly, Sarah Dry, Kristen N. Ganjoo, Ricardo J. Gonzalez, Ashley Holder, Jade Homsi, Vicki Keedy, Ciara M. Kelly, Edward Kim, David Liebner, Martin McCarter, Sean V. McGarry, Nathan W. Mesko, Christian Meyer, Alberto S. Pappo, Amanda M. Parkes, Ivy A. Petersen, Seth M. Pollack, Matthew Poppe, Richard F. Riedel, Scott Schuetze, Jacob Shabason, Jason K. Sicklick, Matthew B. Spraker, Melissa Zimel, Lisa E. Hang, Hema Sundar, and Mary Anne Bergman
) regimen followed by surgery and adjuvant chemotherapy with the same regimen was superior to that of historical controls. 40 The 5-year actuarial local control, freedom from distant metastasis, DFS, and OS rates were 92% and 86% ( P =.1155), 75% and 44
Charles L. Loprinzi and Peter M. Ravdin
References 1 Levine MN Gafni A Markham B . A bedside decision instrument to elicit a patient's preference concerning adjuvant chemotherapy for breast cancer . Ann Intern Med 1992 ; 117 : 53 – 58 . 2 Whelan T. Levine M
Margaret Tempero
for recurrence. The TAILORx study was designed to validate the use of the test in patients with early-stage breast cancer at intermediate risk for recurrence. Based on its findings, 70% of these patients can safely avoid adjuvant chemotherapy. This
Jill A. Foster, Maziar Abdolrasulnia, Hamidreza Doroodchi, Joan McClure, and Linda Casebeer
. 5 Griggs JJ Culakova E Sorbero MF . Social and racial differences in selection of breast cancer adjuvant chemotherapy regimens . J Clin Oncol 2007 : 25 : 2522 – 2527 . 6 Landercasper J Dietrich LL Johnson JM . A breast center
Early-Stage Breast Cancer Expiration Date: 2/18/14 CASE REPORT: Adjuvant Chemotherapy Decisions in Clinical Practice for Early-Stage Node-Negative, Estrogen Receptor-Positive, HER2-Negative Breast Cancer: Challenges and Considerations Expiration
Swaminathan Murugappan, William P. Harris, Christopher G. Willett, and Edward Lin
reduced the local recurrence rate to 5% to 8% when combined with neoadjuvant chemoradiation and adjuvant chemotherapy. 5 , 6 Efforts to improve the current neoadjuvant standard of LARC through integrating newer chemotherapy or molecularly targeted agents
Ernest S. Han and Mark Wakabayashi
addition, the decision to administer adjuvant chemotherapy is determined based on comprehensive surgical staging. Patients with stage IA grade 1 to 2 and IB grade 1 to 2 cancers may undergo observation, whereas patients with stage I grade 3 or stage IC
