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Complications of Multiple Myeloma Therapy, Part 1: Risk Reduction and Management of Peripheral Neuropathy and Asthenia

Paul G. Richardson, Jacob P. Laubach, Robert L. Schlossman, Constantine Mitsiades, and Kenneth Anderson

neuropathy may be detected in 11% to 52% and 39% to 46% of these populations, respectively. 1 – 6 Risk factors for PN include treatment-specific characteristics, such as therapy duration, dose intensity, and cumulative dose, and patient-specific factors

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Risk Stratification and Emerging Treatment Strategies in Acute Myeloid Leukemia

Margaret R. O’Donnell

“In the majority of our patients, the major risk factor for whether they will do well or poorly is related to their cytogenetic and/or molecular markers,” stated Margaret R. O’Donnell, MD, Associate Clinical Director, Division of Hematology and

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Alcohol Use Among Patients With Cancer and Survivors in the United States, 2000–2017

Nina N. Sanford, David J. Sher, Xiaohan Xu, Chul Ahn, Anthony V. D’Amico, Ayal A. Aizer, and Brandon A. Mahal

Background Alcohol use has been identified as a risk factor for several malignancies, including cancers of the head and neck, esophagus, colorectum, liver, and breast. 1 – 3 Epidemiologic studies have shown that higher alcohol consumption over

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Role of Surgery for Locally Advanced and Metastatic Renal Cell Carcinoma

Robert Torrey, Philippe E. Spiess, Sumanta K. Pal, and David Josephson

study from MD Anderson Cancer Center, adverse risk factors were described as positive local recurrence margin, increased size of recurrence, presence of sarcomatoid features, and abnormal serum alkaline phosphatase or lactate dehydrogenase. Patients with

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Radiation Therapy and Breast Cancer Risk

Andrea K. Ng and Lois B. Travis

.9%. 61 Although these excesses are largely related to preexisting breast cancer risk factors, prior radiation therapy, especially treatment at a young age, may contribute to the increased risk. 28 - 30 , 62 In early case-control studies by Storm et al

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Health Behaviors and Quality of Life Among Colorectal Cancer Survivors

Elizabeth A. Rohan, Julie S. Townsend, Temeika L. Fairley, and Sherri L. Stewart

addressed in interventions. Methods Behavioral Risk Factor Surveillance System Survey This study used the Behavioral Risk Factor Surveillance System (BRFSS), a state-based system of health surveys that collects information on health risk

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Pancreatic Adenocarcinoma

Margaret A. Tempero, J. Pablo Arnoletti, Stephen Behrman, Edgar Ben-Josef, Al B. Benson III, Jordan D. Berlin, John L. Cameron, Ephraim S. Casper, Steven J. Cohen, Michelle Duff, Joshua D.I. Ellenhorn, William G. Hawkins, John P. Hoffman, Boris W. Kuvshinoff II, Mokenge P. Malafa, Peter Muscarella II, Eric K. Nakakura, Aaron R. Sasson, Sarah P. Thayer, Douglas S. Tyler, Robert S. Warren, Samuel Whiting, Christopher Willett, and Robert A. Wolff

unanimously endorses participation in a clinical trial as the preferred option over standard or accepted therapy. Risk Factors and Genetic Predisposition Although the associated increase in risk is small, the development of pancreatic cancer is firmly

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Merkel Cell Carcinoma, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology

Christopher K. Bichakjian, Thomas Olencki, Sumaira Z. Aasi, Murad Alam, James S. Andersen, Rachel Blitzblau, Glen M. Bowen, Carlo M. Contreras, Gregory A. Daniels, Roy Decker, Jeffrey M. Farma, Kris Fisher, Brian Gastman, Karthik Ghosh, Roy C. Grekin, Kenneth Grossman, Alan L. Ho, Karl D. Lewis, Manisha Loss, Daniel D. Lydiatt, Jane Messina, Kishwer S. Nehal, Paul Nghiem, Igor Puzanov, Chrysalyne D. Schmults, Ashok R. Shaha, Valencia Thomas, Yaohui G. Xu, John A. Zic, Karin G. Hoffmann, and Anita M. Engh

– 7 , 17 , 19 , 22 , 30 , 31 and depend on stage at presentation. 5 – 7 , 15 , 17 , 19 - 22 , 26 , 30 , 32 – 34 Risk Factors for MCC Sun exposure is believed to be a major risk factor for MCC, based on increased incidence in geographical areas

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Elderly Black Non-Hispanic Patients With Head and Neck Squamous Cell Cancer Have the Worst Survival Outcomes

Jessica D. McDermott, Megan Eguchi, Rustain Morgan, Arya Amini, Julie A. Goddard, Evelinn A. Borrayo, and Sana D. Karam

to the ongoing genius of American medicine.” More than 30 years later, such disparities persist. In this updated SEER-Medicare analysis, Black NH race continues to function as a critical risk factor for worst CSS outcomes in HNC. We identified late

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Real-World Impact of a Decision Support Tool on Colony-Stimulating Factor Use and Chemotherapy-Induced Febrile Neutropenia Among Patients With Breast Cancer

Abiy Agiro, Andrea DeVries, Jennifer Malin, and Michael J. Fisch

Factors recommend febrile neutropenia (FN) prophylaxis using a colony-stimulating factor (CSF) when risk, based on the chemotherapy regimen and patient risk factors, is “high” (>20%). 7 CSF prophylaxis may also be considered based on patient risk factors