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Adjuvant Therapy for Soft Tissue Sarcoma

Scott M. Schuetze and Michael E. Ray

Chang AE Baker AR . Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity . J Clin Oncol 1998 ; 16 : 197 – 203 . 4 Abbas JS Holyoke ED Moore R Karakousis CP

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Treatment Options for Merkel Cell Carcinoma

Samuel W. Beenken and Marshall M. Urist

Meeuwissen JA Bourne RG Kearsley JH . The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma . Int J Radiat Oncol Biol Phys 1995 ; 31 : 325 – 331 . 8 Fenig E Brenner B Katz A . The role of radiation therapy

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Bone Cancer

J. Sybil Biermann, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, James E. Butrynski, David Cheong, Warren Chow, William T. Curry, Deborah A. Frassica, Frank J. Frassica, Kenneth R. Hande, Francis J. Hornicek, Robin L. Jones, Joel Mayerson, Sean V. McGarry, Brian McGrath, Carol D. Morris, Richard J. O'Donnell, R. Lor Randall, Victor M. Santana, Robert L. Satcher, Herrick J. Siegel, Margaret von Mehren, Mary Anne Bergman, and Hema Sundar

with demonstrated expertise in the management of these tumors. Long-term surveillance and follow-up are necessary when considering the risk of recurrence and comorbidities associated with chemotherapy and radiation therapy (RT). Life-long follow-up is

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Central Nervous System Cancers, Version 2.2014

Louis Burt Nabors, Jana Portnow, Mario Ammirati, Henry Brem, Paul Brown, Nicholas Butowski, Marc C. Chamberlain, Lisa M. DeAngelis, Robert A. Fenstermaker, Allan Friedman, Mark R. Gilbert, Jona Hattangadi-Gluth, Deneen Hesser, Matthias Holdhoff, Larry Junck, Ronald Lawson, Jay S. Loeffler, Paul L. Moots, Maciej M. Mrugala, Herbert B. Newton, Jeffrey J. Raizer, Lawrence Recht, Nicole Shonka, Dennis C. Shrieve, Allen K. Sills Jr, Lode J. Swinnen, David Tran, Nam Tran, Frank D. Vrionis, Patrick Yung Wen, Nicole R. McMillian, and Maria Ho

evident on MRI scans. The presenting signs and symptoms of metastatic brain lesions are similar to those of other mass lesions in the brain, such as headache, seizures, and neurologic impairment. Historically, whole-brain radiation therapy (WBRT) and

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Evolving Use of Androgen Deprivation Therapy in Prostate Cancer Management

James L. Mohler

. ADT Plus Radiation Therapy Does radiation therapy (RT) make ADT more effective, and does ADT improve RT? In the phase III EORTC 22991 trial involving 819 patients, 3 the addition of short-term ADT to RT improved biochemical and clinical disease

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NCCN Guidelines Insights: Soft Tissue Sarcoma, Version 1.2021

Featured Updates to the NCCN Guidelines

Margaret von Mehren, John M. Kane III, Marilyn M. Bui, Edwin Choy, Mary Connelly, Sarah Dry, Kristen N. Ganjoo, Suzanne George, Ricardo J. Gonzalez, Martin J. Heslin, Jade Homsi, Vicki Keedy, Ciara M. Kelly, Edward Kim, David Liebner, Martin McCarter, Sean V. McGarry, Christian Meyer, Alberto S. Pappo, Amanda M. Parkes, I. Benjamin Paz, Ivy A. Petersen, Matthew Poppe, Richard F. Riedel, Brian Rubin, Scott Schuetze, Jacob Shabason, Jason K. Sicklick, Matthew B. Spraker, Melissa Zimel, Mary Anne Bergman, and Giby V. George

significant symptoms, intervention is recommended. Treatment options include surgery (if resectable), systemic therapy, definitive radiation therapy (RT), ablation procedures, or surgery with RT. Choice of therapy is dependent upon the anatomic location (ie

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Larotrectinib in a Patient With Advanced Pleomorphic Liposarcoma of the Uterus

Anisley Valenciaga, O. Hans Iwenofu, and Gabriel Tinoco

image of MRI showing hypointense large soft tissue mass (3.1 × 5.3 × 5.0 cm) in the right neck (yellow arrow) while patient was receiving pazopanib prior to radiation therapy. Following radiation, the patient experienced considerable pain in her

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Favorable Early-Stage Hodgkin Lymphoma

Joachim Yahalom

. Radiation therapy in the treatment of Hodgkin's disease: do you see what I see? J Natl Cancer Inst 2003 ; 95 : 928 – 929 . 3. Longo DL . Hodgkin disease: the sword of Damocles resheathed . Blood 2003 ; 104 : 3418 . 4. Longo DL

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NCCN Guidelines® Insights: Squamous Cell Skin Cancer, Version 1.2022

Featured Updates to the NCCN Guidelines

Chrysalyne D. Schmults, Rachel Blitzblau, Sumaira Z. Aasi, Murad Alam, James S. Andersen, Brian C. Baumann, Jeremy Bordeaux, Pei-Ling Chen, Robert Chin, Carlo M. Contreras, Dominick DiMaio, Jessica M. Donigan, Jeffrey M. Farma, Karthik Ghosh, Roy C. Grekin, Kelly Harms, Alan L. Ho, Ashley Holder, John Nicholas Lukens, Theresa Medina, Kishwer S. Nehal, Paul Nghiem, Soo Park, Tejesh Patel, Igor Puzanov, Jeffrey Scott, Aleksandar Sekulic, Ashok R. Shaha, Divya Srivastava, William Stebbins, Valencia Thomas, Yaohui G. Xu, Beth McCullough, Mary A. Dwyer, and Mai Q. Nguyen

rates of recurrence (6.8%–32.3%) in studies that occasionally include basal cell carcinoma as well as treatment with radiation therapy (RT). 23 – 28 Risk factors associated with metastasis after Mohs include size >2 cm, Clark level (metastatic CSCC are

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Local Treatment of Malignant Brain Tumors Using Implantable Chemotherapeutic Polymers

Gary L. Gallia, Steven Brem, and Henry Brem

Schoenfeld D . Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study