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. Constipation, nausea and vomiting, pruritus, delirium, respiratory depression, motor and cognitive impairment, and sedation are fairly common, especially when multiple agents are used. 84 - 89 Each adverse effect requires a careful assessment and treatment

broader multidimensional assessment. 3 , 4 , 25 , 26 Cancer-specific HRQOL questionnaires, such as the Functional Assessment of Cancer Therapy-General (FACT-G 4 ) and EORTC QLQ-C30, 3 assess common cancer symptoms such as pain, fatigue, and nausea in

9 (82%) of 11 patients with advanced cancer were successfully treated for cancer-related fatigue with methylphenidate. Notably, more than half of the patients experienced side effects, such as insomnia, agitation, anorexia, dry mouth, nausea, and

thalidomide treatment; if present, it is usually mild in severity. 9 , 14 Autonomic manifestations are common, and include gastrointestinal (e.g., constipation, anorexia, nausea) as well as cardiovascular (e.g., hypotension, bradycardia) effects. 15 – 17

associated with ED visits and found that pain, nausea, and shortness of breath were significantly associated. 12 Additionally, as symptom severity increased, the odds of visiting the ED increased further. 12 PROs are routinely collected throughout Alberta

cramping), cardiac (arrhythmia, hypertension, palpitations), nail/hair/skin changes, cytopenias, gastrointestinal (diarrhea, nausea, reflux), and bleeding/bruising. In 65% of cases, the adverse effect improved or resolved after the initial dose reduction

boundaries. Responses will prompt the delivery of tailored education across platforms, such as the release of an educational video to a patient’s iPad that outlines the management of nausea. Data obtained from patients are made available to the physician at

immunotherapy (eg, nausea, fatigue), and when they do occur, are typically less than grade 3. Immunotoxicity, however, is associated with checkpoint inhibitors. Most of the immune-related AEs are due to inflammation of organ systems and end in “-itis.” They are

practice by following up with these patients a few weeks after starting medication to assess their progress and tolerance. Nausea and other gastrointestinal symptoms are the most common AEs associated with varenicline. Combination Therapies Studies

Aspects of Comfort: Management of Pain, Fatigue and Nausea . New York : Springer ; 1989 : 199 – 208 . 18. Belza BL . Comparison of self-reported fatigue in rheumatoid arthritis and controls . J Rheumatol 1995 ; 22 : 639 – 643 . 19