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Matthew Ulrickson, Fred Okuku, Victoria Walusansa, Oliver Press, Sam Kalungi, David Wu, Fred Kambugu, Corey Casper, and Jackson Orem

Mulago Hospital reporting a 7-year history of gradually increasing pruritus and diffuse, scaly skin lesions ( Figure 1A ). More recently he reported mild weight loss and anorexia, although he denied having drenching night-sweats or fevers. He denied any

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Stacey Shiovitz and Keith D. Eaton

Case Report A 66-year-old woman presented with newly diagnosed stage IV non–small cell lung cancer (NSCLC) and a large adrenal metastasis. Five weeks before presentation, she developed low-grade fevers and shortness of breath with minimal

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Chelsea C. Pinnix, Valerie Reed, and Bouthaina Dabaja

abdominal pain resolved after recent administration of a proton pump inhibitor. She denied gastrointestinal symptoms. She denied melena, nausea, vomiting, anorexia, unintentional weight loss, fevers, and night sweats. Her medical history was notable for HT

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Rajinder S. Grover, Kemp Kernstine, and Amrita Krishnan

56-year-old woman noted a slowly enlarging right parotid mass for approximately 2 months. She denied any fever, night sweats, decreased salivation, dry eyes, pain, or facial paresthesias. She had an intentional weight loss of about 19 pounds over the

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Daniel C. McFarland, Heather Polizzi, John Mascarenhas, Marina Kremyanskaya, Jimmie Holland, and Ronald Hoffman

pain (43%), fevers (13%), weight loss (10%), and splenic pain (4%). MPN-associated symptom burden and inability to perform activities of daily living (ADLs) were associated with worsening cytopenias and splenomegaly. 5 However, distress, anxiety, and

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Ruben Mesa, Catriona Jamieson, Ravi Bhatia, Michael W. Deininger, Aaron T. Gerds, Ivana Gojo, Jason Gotlib, Krishna Gundabolu, Gabriela Hobbs, Rebecca B. Klisovic, Patricia Kropf, Sanjay R. Mohan, Stephen Oh, Eric Padron, Nikolai Podoltsev, Daniel A. Pollyea, Raajit Rampal, Lindsay A. M. Rein, Bart Scott, David S. Snyder, Brady L. Stein, Srdan Verstovsek, Martha Wadleigh, Eunice S. Wang, Mary Anne Bergman, Kristina M. Gregory, and Hema Sundar

daily living. 2 , 3 Constitutional symptoms (fever, night sweats, and weight loss) are more frequently reported in patients with MF compared with those with PV or ET. 2 , 42 In a recent landmark survey that evaluated the symptom burden experienced by

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Juliana E. Hidalgo Lopez, Mariko Yabe, Adrian A. Carballo-Zarate, Sa A. Wang, Jeffrey L. Jorgensen, Sairah Ahmed, John Lee, Shaoying Li, Ellen Schlette, Timothy McDonnell, Roberto N. Miranda, L. Jeffrey Medeiros, Carlos E. Bueso-Ramos, and C. Cameron Yin

-LGL leukemia and T-LGL proliferation and other lymphoproliferative disorders after SCT is proposed. Case Report A 16-year-old man initially presented to another hospital with fever, weight loss, lymphadenopathy, and hepatosplenomegaly in October 2012. A

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Venkata K. Pokuri, Mihai Merzianu, Shipra Gandhi, Junaid Baqai, Thom R. Loree, and Seema Bhat

marrow, and gastrointestinal tract); the remaining patients presented with both nodal and extranodal disease. 8 Systemic symptoms (fever, night sweats, weight loss, and fatigue) were uncommon and mostly occurred in patients with both nodal and extranodal

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Iulia Giuroiu and Diane Reidy-Lagunes

important to minimize treatment-related adverse effects, which can include pain, nausea, fever, fatigue, and liver abnormalities. Systemic Cytotoxic Therapy Treatment No clearly defined role currently exists for conventional chemotherapy in the

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Nora Janjan

be better for other physical symptoms, such as fever, and the absence of a symptom. 22 , 23 Data capture of PROs enables health care providers to evaluate the adequacy of CRP control, especially that of breakthrough pain, for individual patients