The Process of NCCN Guidelines™ Adaptation to the Middle East and North Africa Region

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  • a From the Department of Oncology, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia; Department of Oncology, Cairo University, Cairo, Egypt; National Comprehensive Cancer Network, Fort Washington, Pennsylvania; and Aptium Oncology, Lynn Cancer Institute, Boca Raton, Florida, and University of Tennessee, Memphis, Tennessee.
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The NCCN developed clinical practice guidelines for oncology that set the standard of cancer care in the United States. Because of wide acceptance of, need for, and interest in standardized treatment practices across the world, NCCN launched initiatives to help international groups adapt these guidelines. This article describes the initiative in the Middle East and North Africa (MENA) region. A group of oncology experts and key opinion leaders were assembled into 7 specific committees to develop treatment guidelines for breast cancer, lung cancer, colon cancer, prostate cancer, hepatobiliary cancer, lymphoma, and palliative care. The committees reviewed the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) to identify any modifications required for them to be more applicable to the MENA region based on available evidence and regional experience. These modifications were discussed with NCCN experts and summarized for each specific area. The development of these guidelines generated a strong interest in the region to develop more evidence-based practice and create further networking and collaboration.

Correspondence: Abdul-Rahman Jazieh, MD, MPH, Department of Oncology, Mail Code 1777, P.O. Box 22490, Riyadh 11426, Kingdom of Saudi Arabia. E-mail:
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