Management of Advanced Gastroenteropancreatic Neuroendocrine Tumors
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Neuroendocrine neoplasms (NENs) comprise a diverse group of tumors that can arise throughout the body, making classification and treatment particularly complex. The NCCN Guidelines for Neuroendocrine and Adrenal Tumors have expanded to include treatment options based on the location, stage, and grade of the tumor, However, these treatment approaches rely on accurate pathologic classification of the tumor and correlation with imaging and clinical features. With a growing list of available systemic treatment options for advanced tumors and a disease continuum often measured in years, if not decades in some patients, treatment sequencing, quality of life, and potential long-term side effects remain important considerations.
Disclosures: Dr. Bergsland has disclosed receiving grant/research support from Boehringer Ingelheim GmbH, Merck & Co., Inc., and RayzeBio, Inc.
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