Letter to the Editor: Advancing Prognostic Stratification in PSCC: Developing Predictive Models as the Next Pivotal Step

Authors:
Matthias May Department of Urology, St. Elisabeth Hospital Straubing, Brothers of Mercy Hospital, Straubing, Germany

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 MD, PhD
,
Jan Hrudka Department of Pathology, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic

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 MD
,
Laura Elst Department of Urology, University Hospitals Leuven, Leuven, Belgium

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Sigrid Regauer Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria

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 MD, PhD
Volume/Issue:
Volume 23: Issue 5
Online Publication Date:
May 2025
DOI:
https://doi.org/10.6004/jnccn.2025.7038
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Print ISSN:
1540-1405
Online ISSN:
1540-1413
Publisher:
National Comprehensive Cancer Network
Cover Journal of the National Comprehensive Cancer Network
  • 1.

    Mustasam A, Parza K, Ionescu F, et al. The prognostic role of HPV or p16INK4a status in penile squamous cell carcinoma: a meta-analysis. J Natl Compr Canc Netw 2025;23:e247078.

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  • 2.

    Lebentrau S, Wolff I, Hempel MC, et al. Knowledge of German-speaking urologists regarding the association between penile cancer and human papilloma virus: results of a survey of the European PROspective Penile Cancer Study (E-PROPS). Aktuelle Urol 2022;53:461–467.

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  • 3.

    Ermakov MS, Kashofer K, Regauer S. Different mutational landscapes in human papillomavirus-induced and human papillomavirus-independent invasive penile squamous cell cancers. Mod Pathol 2023;36:100250.

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  • 4.

    Elst L, Philips G, Vandermaesen K, et al. Single-cell atlas of penile cancer reveals TP53 mutations as a driver of an aggressive phenotype, irrespective of human papillomavirus status, and provides clues for treatment personalization. Eur Urol 2024;86:114–127.

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  • 5.

    Hrudka J, Prouzová Z, Kendall Bártů M, et al. Immune cell infiltration, tumour budding, and the p53 expression pattern are important predictors in penile squamous cell carcinoma: a retrospective study of 152 cases. Pathology 2023;55:637–649.

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Copyright:
Copyright © 2025 by the National Comprehensive Cancer Network 2025
Article Category:
Letter
Print Publication Date:
01 May 2025
Online Publication Date:
May 2025

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