Authors’ Reply to the Letter to the Editor by Suarez-Kurtz: Tailoring and Standardizing DPYD Genotyping Tests to Promote Equity in Pharmacogenomics

Authors:
Jai N. Patel Division of Cancer Pharmacology & Pharmacogenomics, Levine Cancer Institute, Atrium Health, Charlotte, NC
Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC

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Sarah A. Morris Division of Cancer Pharmacology & Pharmacogenomics, Levine Cancer Institute, Atrium Health, Charlotte, NC

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D. Grace Nguyen Division of Cancer Pharmacology & Pharmacogenomics, Levine Cancer Institute, Atrium Health, Charlotte, NC

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Volume/Issue:
Volume 22: Issue 8
Online Publication Date:
Oct 2024
DOI:
https://doi.org/10.6004/jnccn.2024.7073
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Print ISSN:
1540-1405
Online ISSN:
1540-1413
Publisher:
National Comprehensive Cancer Network
Cover Journal of the National Comprehensive Cancer Network
  • 1.

    O’Donnell PH, Dolan ME. Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy. Clin Cancer Res 2009;15:4806–4814.

  • 2.

    Suarez-Kurtz G. Letter to the editor: variant coverage and diagnostic performance of commercially available DPYD genotyping tests in Brazil. J Natl Compr Canc Netw 2024;22:e247059.

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  • 3.

    Pratt VM, Cavallari LH, Fulmer ML, et al. DPYD genotyping recommendations. J Mol Diagn. Published online July 18, 2024. doi:10.1016/j.jmoldx.2024.05.015

  • 4.

    Offer SM, Lee AM, Mattison LK, et al. A DPYD variant (Y186C) in individuals of African ancestry is associated with reduced DPD enzyme activity. Clin Pharmacol Ther 2013;94:158–166.

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  • 5.

    Chan TH, Zhang JE, Pirmohamed M. DPYD genetic polymorphisms in non-European patients with severe fluoropyrimidine-related toxicity: a systematic review. Br J Cancer 2024;131:498–514.

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  • 6.

    Shriver SP, Adams D, McKelvey BA, et al. Overcoming barriers to discovery and implementation of equitable pharmacogenomic testing in oncology. J Clin Oncol 2024;42:1181–1192.

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Copyright:
Copyright © 2024 by the National Comprehensive Cancer Network 2024
Article Category:
Reply
Print Publication Date:
01 Oct 2024
Online Publication Date:
Oct 2024

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