NCCN Policy Summit: Reducing the Cancer Burden Through Prevention and Early Detection

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Lindsey Bandini National Comprehensive Cancer Network

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Alyssa Schatz National Comprehensive Cancer Network

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Victoria Hood National Comprehensive Cancer Network

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Nikia Clark Roswell Park Comprehensive Cancer Center

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Michael J. Hall Fox Chase Cancer Center

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Robert W. Carlson National Comprehensive Cancer Network

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Cancer prevention, screening, and early detection play an integral role in cancer incidence and outcomes. It is estimated that 30% to 50% of cancers worldwide are preventable, and it is well established that early detection of many cancers is associated with improved treatment outcomes. A recent NCCN Policy Summit: Reducing the Cancer Burden Through Prevention and Early Detection brought together healthcare providers, payers, policymakers, patient advocates, industry representatives, and technology representatives to explore challenges, triumphs, and outstanding questions surrounding current practices. Keynotes were delivered by Dr. Lisa Richardson, Director of the Division of Cancer Prevention and Control within the CDC, and Dr. Danielle Carnival, White House Cancer Moonshot Coordinator. Dr. Richardson focused on the field of public health, translating its utility in preventing and diagnosing cancer in the United States, while Dr. Carnival discussed ambitious goals by the Cancer Moonshot in reducing the cancer burden. Panelists highlighted characteristics of high-impact prevention and early detection programs, including how genetic testing has impacted this space. Existing programs are often challenged due to limitations in data, as well as financial, structural, and social barriers to motivating individuals to act on recommendations. Despite these barriers, we can learn from highly successful programs and should apply proven attributes, such as community engagement, more broadly.

Submitted April 17, 2023; final revision received May 26, 2023; accepted for publication May 31, 2023.

Disclosures: M.J. Hall has disclosed serving on an advisory board for Natera, and participating in research with Caris Life Sciences, Myriad Genetics, Invitae, and Ambry Genetics. L. Bandini, A. Schatz, V. Hood, and R.W. Carlson have disclosed being employed by NCCN. N. Clark has disclosed having no financial interests, arrangements, affiliations, or commercial interests with the manufacturers of any products discussed in this article or their competitors.

Correspondence: Lindsey Bandini, MPH, National Comprehensive Cancer Network, 3025 Chemical Road, Suite 100, Plymouth Meeting, PA 19462. Email: bandini@nccn.org

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