Smoking Cessation, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology

Authors:
Peter G. ShieldsThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

Search for other papers by Peter G. Shields in
Current site
Google Scholar
PubMed
Close
 MD
,
Laura BierutSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Search for other papers by Laura Bierut in
Current site
Google Scholar
PubMed
Close
 MD
,
Douglas ArenbergUniversity of Michigan Rogel Cancer Center

Search for other papers by Douglas Arenberg in
Current site
Google Scholar
PubMed
Close
 MD
,
David BalisUT Southwestern Simmons Comprehensive Cancer Center

Search for other papers by David Balis in
Current site
Google Scholar
PubMed
Close
 MD
,
Paul M. CinciripiniThe University of Texas MD Anderson Cancer Center

Search for other papers by Paul M. Cinciripini in
Current site
Google Scholar
PubMed
Close
 PhD
,
James DavisDuke Cancer Institute

Search for other papers by James Davis in
Current site
Google Scholar
PubMed
Close
 MD
,
Donna EdmondsonFox Chase Cancer Center

Search for other papers by Donna Edmondson in
Current site
Google Scholar
PubMed
Close
 MSN, CRNP
,
Joy FelicianoThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Search for other papers by Joy Feliciano in
Current site
Google Scholar
PubMed
Close
 MD
,
Brian HitsmanRobert H. Lurie Comprehensive Cancer Center of Northwestern University

Search for other papers by Brian Hitsman in
Current site
Google Scholar
PubMed
Close
 PhD
,
Karen S. HudmonIndiana University Melvin and Bren Simon Comprehensive Cancer Center

Search for other papers by Karen S. Hudmon in
Current site
Google Scholar
PubMed
Close
 DrPH, MS, BS
,
Michael T. JaklitschDana-Farber/Brigham and Women’s Cancer Center

Search for other papers by Michael T. Jaklitsch in
Current site
Google Scholar
PubMed
Close
 MD
,
Frank T. LeoneAbramson Cancer Center at the University of Pennsylvania

Search for other papers by Frank T. Leone in
Current site
Google Scholar
PubMed
Close
 MD, MS
,
Pamela LingUCSF Helen Diller Family Comprehensive Cancer Center

Search for other papers by Pamela Ling in
Current site
Google Scholar
PubMed
Close
 MD
,
Danielle E. McCarthyUniversity of Wisconsin Carbone Cancer Center

Search for other papers by Danielle E. McCarthy in
Current site
Google Scholar
PubMed
Close
 PhD
,
Michael K. OngUCLA Jonsson Comprehensive Cancer Center

Search for other papers by Michael K. Ong in
Current site
Google Scholar
PubMed
Close
 MD, PhD
,
Elyse R. ParkMassachusetts General Hospital Cancer Center

Search for other papers by Elyse R. Park in
Current site
Google Scholar
PubMed
Close
 PhD, MPH
,
Judith ProchaskaStanford Cancer Institute

Search for other papers by Judith Prochaska in
Current site
Google Scholar
PubMed
Close
 PhD, MPH
,
Argelia J. SandovalCity of Hope National Medical Center

Search for other papers by Argelia J. Sandoval in
Current site
Google Scholar
PubMed
Close
 MD
,
Christine E. ShefferRoswell Park Comprehensive Cancer Center

Search for other papers by Christine E. Sheffer in
Current site
Google Scholar
PubMed
Close
 PhD
,
Sharon SpencerO’Neal Comprehensive Cancer Center at UAB

Search for other papers by Sharon Spencer in
Current site
Google Scholar
PubMed
Close
 MD
,
Jamie L. StudtsUniversity of Colorado Cancer Center

Search for other papers by Jamie L. Studts in
Current site
Google Scholar
PubMed
Close
 PhD
,
Tawee TanvetyanonMoffitt Cancer Center

Search for other papers by Tawee Tanvetyanon in
Current site
Google Scholar
PubMed
Close
 MD, MPH
,
Hilary A. TindleVanderbilt-Ingram Cancer Center

Search for other papers by Hilary A. Tindle in
Current site
Google Scholar
PubMed
Close
 MD, MPH
,
Elisa TongUC Davis Comprehensive Cancer Center

Search for other papers by Elisa Tong in
Current site
Google Scholar
PubMed
Close
 MD, MA
,
Matthew TripletteFred Hutchinson Cancer Center

Search for other papers by Matthew Triplette in
Current site
Google Scholar
PubMed
Close
 MD, MPH
,
James UrbanicUC San Diego Moores Cancer Center

Search for other papers by James Urbanic in
Current site
Google Scholar
PubMed
Close
 MD
,
Gregory VideticCase Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

Search for other papers by Gregory Videtic in
Current site
Google Scholar
PubMed
Close
 MD
,
David WarnerMayo Clinic Cancer Center

Search for other papers by David Warner in
Current site
Google Scholar
PubMed
Close
 MD
,
C. Will WhitlockMemorial Sloan Kettering Cancer Center

Search for other papers by C. Will Whitlock in
Current site
Google Scholar
PubMed
Close
 NP, RN
,
Beth McCulloughNational Comprehensive Cancer Network

Search for other papers by Beth McCullough in
Current site
Google Scholar
PubMed
Close
 RN, BS
, and
Susan DarlowNational Comprehensive Cancer Network

Search for other papers by Susan Darlow in
Current site
Google Scholar
PubMed
Close
 PhD
Restricted access

Although the harmful effects of smoking after a cancer diagnosis have been clearly demonstrated, many patients continue to smoke cigarettes during treatment and beyond. The NCCN Guidelines for Smoking Cessation emphasize the importance of smoking cessation in all patients with cancer and seek to establish evidence-based recommendations tailored to the unique needs and concerns of patients with cancer. The recommendations contained herein describe interventions for cessation of all combustible tobacco products (eg, cigarettes, cigars, hookah), including smokeless tobacco products. However, recommendations are based on studies of cigarette smoking. The NCCN Smoking Cessation Panel recommends that treatment plans for all patients with cancer who smoke include the following 3 tenets that should be done concurrently: (1) evidence-based motivational strategies and behavior therapy (counseling), which can be brief; (2) evidence-based pharmacotherapy; and (3) close follow-up with retreatment as needed.

Individual Disclosures for the NCCN Smoking Cessation Panel
Individual Disclosures for the NCCN Smoking Cessation Panel

  • Collapse
  • Expand
  • 1.

    Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin 2019;69:734.

  • 2.

    CDC. CDC Vital Signs: Cancer and tobacco use. Accessed January 12, 2023. Available at: https://www.cdc.gov/vitalsigns/pdf/2016-11-vitalsigns.pdf

    • Search Google Scholar
    • Export Citation
  • 3.

    Lortet-Tieulent J, Goding Sauer A, Siegel RL, et al. State-level cancer mortality attributable to cigarette smoking in the United States. JAMA Intern Med 2016;176:17921798.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022. CA Cancer J Clin 2022;72:733.

  • 5.

    Tao L, Wang R, Gao YT, et al. Impact of postdiagnosis smoking on long-term survival of cancer patients: the Shanghai cohort study. Cancer Epidemiol Biomarkers Prev 2013;22:24042411.

    • Search Google Scholar
    • Export Citation
  • 6.

    Passarelli MN, Newcomb PA, Hampton JM, et al. Cigarette smoking before and after breast cancer diagnosis: mortality from breast cancer and smoking-related diseases. J Clin Oncol 2016;34:13151322.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    U.S. Department of Health & Human Services. The health consequences of smoking—50 years of progress: a report of the surgeon general. Accessed January 23, 2023. Available at: https://www.hhs.gov/sites/default/files/consequences-smoking-exec-summary.pdf

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Warren GW, Cartmell KB, Garrett-Mayer E, et al. Attributable failure of first-line cancer treatment and incremental costs associated with smoking by patients with cancer. JAMA Netw Open 2019;2:e191703.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    Underwood JM, Townsend JS, Tai E, et al. Persistent cigarette smoking and other tobacco use after a tobacco-related cancer diagnosis. J Cancer Surviv 2012;6:333344.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Parsons A, Daley A, Begh R, et al. Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: systematic review of observational studies with meta-analysis. BMJ 2010;340:b5569.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Warren GW, Kasza KA, Reid ME, et al. Smoking at diagnosis and survival in cancer patients. Int J Cancer 2013;132:401410.

  • 12.

    Dobson Amato KA, Hyland A, Reed R, et al. Tobacco cessation may improve lung cancer patient survival. J Thorac Oncol 2015;10:10141019.

  • 13.

    Sheikh M, Mukeriya A, Shangina O, et al. Postdiagnosis smoking cessation and reduced risk for lung cancer progression and mortality: a prospective cohort study. Ann Intern Med 2021;174:12321239.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14.

    Baser S, Shannon VR, Eapen GA, et al. Smoking cessation after diagnosis of lung cancer is associated with a beneficial effect on performance status. Chest 2006;130:17841790.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    Carroll AJ, Veluz-Wilkins AK, Blazekovic S, et al. Cancer-related disease factors and smoking cessation treatment: analysis of an ongoing clinical trial. Psychooncology 2018;27:471476.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Gritz ER, Fingeret MC, Vidrine DJ, et al. Successes and failures of the teachable moment: smoking cessation in cancer patients. Cancer 2006;106:1727.

  • 17.

    Westmaas JL, Newton CC, Stevens VL, et al. Does a recent cancer diagnosis predict smoking cessation? An analysis from a large prospective US cohort. J Clin Oncol 2015;33:16471652.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18.

    Tang MW, Oakley R, Dale C, et al. A surgeon led smoking cessation intervention in a head and neck cancer centre. BMC Health Serv Res 2014;14:636.

    • Search Google Scholar
    • Export Citation
  • 19.

    Stead LF, Buitrago D, Preciado N, et al. Physician advice for smoking cessation. Cochrane Database Syst Rev 2013;2013:CD000165.

  • 20.

    Coleman T. Use of simple advice and behavioural support. BMJ 2004;328:397399.

  • 21.

    Aveyard P, Begh R, Parsons A, et al. Brief opportunistic smoking cessation interventions: a systematic review and meta-analysis to compare advice to quit and offer of assistance. Addiction 2012;107:10661073.

    • Search Google Scholar
    • Export Citation
  • 22.

    Lee SM, Landry J, Jones PM, et al. The effectiveness of a perioperative smoking cessation program: a randomized clinical trial. Anesth Analg 2013;117:605613.

    • Search Google Scholar
    • Export Citation
  • 23.

    Stead LF, Hartmann-Boyce J, Perera R, et al. Telephone counselling for smoking cessation. Cochrane Database Syst Rev 2013;8:CD002850.

  • 24.

    Lichtenstein E, Zhu SH, Tedeschi GJ. Smoking cessation quitlines: an underrecognized intervention success story. Am Psychol 2010;65:252261.

  • 25.

    CDC. American Indians/Alaska Natives and tobacco use: health disparities and ways to advance health equity. Accessed January 12, 2023. Available at: https://www.cdc.gov/tobacco/disparities/american-indians/index.htm

    • Search Google Scholar
    • Export Citation
  • 26.

    Toll BA, Brandon TH, Gritz ER, et al. Assessing tobacco use by cancer patients and facilitating cessation: an American Association for Cancer Research policy statement. Clin Cancer Res 2013;19:19411948.

    • Search Google Scholar
    • Export Citation
  • 27.

    Land SR, Toll BA, Moinpour CM, et al. Research priorities, measures, and recommendations for assessment of tobacco use in clinical cancer research. Clin Cancer Res 2016;22:19071913.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28.

    Goldstein AO, Ripley-Moffitt CE, Pathman DE, et al. Tobacco use treatment at the U.S. National Cancer Institute’s designated Cancer Centers. Nicotine Tob Res 2013;15:5258.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 29.

    Peters EN, Torres E, Toll BA, et al. Tobacco assessment in actively accruing National Cancer Institute Cooperative Group Program clinical trials. J Clin Oncol 2012;30:28692875.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 30.

    Siegel DA, Henley SJ, Wike JM, et al. Capture of tobacco use among population-based registries: findings from 10 National Program of Cancer Registries states. Cancer 2018;124:23812389.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31.

    Gritz ER, Dresler C, Sarna L. Smoking, the missing drug interaction in clinical trials: ignoring the obvious. Cancer Epidemiol Biomarkers Prev 2005;14:22872293.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32.

    Warren GW, Marshall JR, Cummings KM, et al. Automated tobacco assessment and cessation support for cancer patients. Cancer 2014;120:562569.

  • 33.

    Baker TB, Piper ME, McCarthy DE, et al. Time to first cigarette in the morning as an index of ability to quit smoking: implications for nicotine dependence. Nicotine Tob Res 2007;9(Suppl 4):S555570.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 34.

    Heatherton TF, Kozlowski LT, Frecker RC, et al. The Fagerström test for nicotine dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict 1991;86:11191127.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 35.

    Chapple A, Ziebland S, McPherson A. Stigma, shame, and blame experienced by patients with lung cancer: qualitative study. BMJ 2004;328:1470.

  • 36.

    Miller WR, Rollnick S. Motivational Interviewing: Preparing People for Change. 3rd ed. The Guilford Press; 2012.

  • 37.

    Rollnick S, Miller WR, Butler CC. Motivational Interviewing in Health Care: Helping Patients Change Behavior. 1st ed. The Guilford Press; 2007.

    • Search Google Scholar
    • Export Citation
  • 38.

    Prochaska JO, Velicer WF. The transtheoretical model of health behavior change. Am J Health Promot 1997;12:3848.

  • 39.

    Lindson-Hawley N, Hartmann-Boyce J, Fanshawe TR, et al. Interventions to reduce harm from continued tobacco use. Cochrane Database Syst Rev 2016;10:CD005231.

  • 40.

    Leone FT, Zhang Y, Evers-Casey S, et al. Initiating pharmacologic treatment in tobacco-dependent adults. An official American Thoracic Society clinical practice guideline. Am J Respir Crit Care Med 2020;202:e531.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 41.

    Lindson-Hawley N, Aveyard P, Hughes JR. Reduction versus abrupt cessation in smokers who want to quit. Cochrane Database Syst Rev 2012;11:CD008033.

  • 42.

    Lindson-Hawley N, Aveyard P, Hughes JR. Gradual reduction vs abrupt cessation as a smoking cessation strategy in smokers who want to quit. JAMA 2013;310:9192.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 43.

    Ostroff JS, Burkhalter JE, Cinciripini PM, et al. Randomized trial of a presurgical scheduled reduced smoking intervention for patients newly diagnosed with cancer. Health Psychol 2014;33:737747.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 44.

    Cather C, Pachas GN, Cieslak KM, et al. Achieving smoking cessation in individuals with schizophrenia: special considerations. CNS Drugs 2017;31:471481.

  • 45.

    Reid MS, Jiang H, Fallon B, et al. Smoking cessation treatment among patients in community-based substance abuse rehabilitation programs: exploring predictors of outcome as clues toward treatment improvement. Am J Drug Alcohol Abuse 2011;37:472478.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 46.

    Ditre JW, Heckman BW, LaRowe LR, et al. Pain status as a predictor of smoking cessation initiation, lapse, and relapse. Nicotine Tob Res 2021;23:186194.

  • 47.

    Vijayaraghavan M, Penko J, Vittinghoff E, et al. Smoking behaviors in a community-based cohort of HIV-infected indigent adults. AIDS Behav 2014;18:535543.

    • Search Google Scholar
    • Export Citation
  • 48.

    Ehlers SL, Bronars CA, Patten CA, et al. Accuracy of self-reported tobacco use status among hematopoietic SCT patients. Bone Marrow Transplant 2014;49:961965.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 49.

    Hald J, Overgaard J, Grau C. Evaluation of objective measures of smoking status--a prospective clinical study in a group of head and neck cancer patients treated with radiotherapy. Acta Oncol 2003;42:154159.

    • Search Google Scholar
    • Export Citation
  • 50.

    Warren GW, Arnold SM, Valentino JP, et al. Accuracy of self-reported tobacco assessments in a head and neck cancer treatment population. Radiother Oncol 2012;103:4548.

    • Search Google Scholar
    • Export Citation
  • 51.

    Kotz D, Brown J, West R. ‘Real-world’ effectiveness of smoking cessation treatments: a population study. Addiction 2014;109:491499.

  • 52.

    Stead LF, Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. Cochrane Database Syst Rev 2012;10:CD008286.

  • 53.

    Stead LF, Koilpillai P, Lancaster T. Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation. Cochrane Database Syst Rev 2015;10:CD009670.

    • Search Google Scholar
    • Export Citation
  • 54.

    Ferguson SG, Shiffman S, Gitchell JG. Nicotine replacement therapies: patient safety and persistence. Patient Relat Outcome Meas 2011;2:111117.

  • 55.

    Leyro TM, Hall SM, Hickman N, et al. Clinical management of tobacco dependence in inpatient psychiatry: provider practices and patient utilization. Psychiatr Serv 2013;64:11611165.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 56.

    Shiffman S. Use of more nicotine lozenges leads to better success in quitting smoking. Addiction 2007;102:809814.

  • 57.

    Crawford G, Weisbrot J, Bastian J, et al. Predictors of varenicline adherence among cancer patients treated for tobacco dependence and its association with smoking cessation. Nicotine Tob Res 2018;21:11351139.

    • Search Google Scholar
    • Export Citation
  • 58.

    Schnoll RA, Goelz PM, Veluz-Wilkins A, et al. Long-term nicotine replacement therapy: a randomized clinical trial. JAMA Intern Med 2015;175:504511.

  • 59.

    Hughes JR. Dependence potential and abuse liability of nicotine replacement therapies. Biomed Pharmacother 1989;43:1117.

  • 60.

    Moore TJ, Furberg CD, Glenmullen J, et al. Suicidal behavior and depression in smoking cessation treatments. PLoS One 2011;6:e27016.

  • 61.

    Thomas KH, Martin RM, Davies NM, et al. Smoking cessation treatment and risk of depression, suicide, and self harm in the Clinical Practice Research Datalink: prospective cohort study. BMJ 2013;347:f5704.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 62.

    Thomas KH, Martin RM, Knipe DW, et al. Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis. BMJ 2015;350:h1109.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 63.

    Hollands GJ, McDermott MS, Lindson-Hawley N, et al. Interventions to increase adherence to medications for tobacco dependence. Cochrane Database Syst Rev 2015;2015:CD009164.

    • Search Google Scholar
    • Export Citation
  • 64.

    Pacek LR, McClernon FJ, Bosworth HB. Adherence to pharmacological smoking cessation interventions: a literature review and synthesis of correlates and barriers. Nicotine Tob Res 2018;20:11631172.

    • Search Google Scholar
    • Export Citation
  • 65.

    Peng AR, Swardfager W, Benowitz NL, et al. Impact of early nausea on varenicline adherence and smoking cessation. Addiction 2020;115:134144.

  • 66.

    Cahill K, Stevens S, Perera R, et al. Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev 2013;2013:CD009329.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 67.

    Coe JW, Brooks PR, Vetelino MG, et al. Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem 2005;48:34743477.

  • 68.

    Mills EJ, Wu P, Lockhart I, et al. Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis. Ann Med 2012;44:588597.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 69.

    Cahill K, Stead LF, Lancaster T. Nicotine receptor partial agonists for smoking cessation. Cochrane Database Syst Rev 2012;4:CD006103.

  • 70.

    Livingstone-Banks J, Lindson N, Hartmann-Boyce J, et al. Effects of interventions to combat tobacco addiction: Cochrane update of 2019 and 2020 reviews. Addiction 2022;117:15731588.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 71.

    Anthenelli RM, Benowitz NL, West R, et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet 2016;387:25072520.

    • Search Google Scholar
    • Export Citation
  • 72.

    Price S, Hitsman B, Veluz-Wilkins A, et al. The use of varenicline to treat nicotine dependence among patients with cancer. Psychooncology 2017;26:15261534.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 73.

    Ebbert JO, Hughes JR, West RJ, et al. Effect of varenicline on smoking cessation through smoking reduction: a randomized clinical trial. JAMA 2015;313:687694.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 74.

    Tonstad S, Tønnesen P, Hajek P, et al. Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial. JAMA 2006;296:6471.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 75.

    Baker TB, Piper ME, Smith SS, et al. Effects of combined varenicline with nicotine patch and of extended treatment duration on smoking cessation: a randomized clinical trial. JAMA 2021;326:14851493.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 76.

    Gonzales D, Hajek P, Pliamm L, et al. Retreatment with varenicline for smoking cessation in smokers who have previously taken varenicline: a randomized, placebo-controlled trial. Clin Pharmacol Ther 2014;96:390396.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 77.

    Hajek P, McRobbie H, Myers Smith K, et al. Increasing varenicline dose in smokers who do not respond to the standard dosage: a randomized clinical trial. JAMA Intern Med 2015;175:266271.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 78.

    Karam-Hage M, Kypriotakis G, Robinson JD, et al. Improvement of smoking abstinence rates with increased varenicline dosage: a propensity score-matched analysis. J Clin Psychopharmacol 2018;38:3441.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 79.

    Jiménez-Ruiz CA, Barrios M, Peña S, et al. Increasing the dose of varenicline in patients who do not respond to the standard dose. Mayo Clin Proc 2013;88:14431445.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 80.

    Jorenby DE, Hays JT, Rigotti NA, et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006;296:5663.

    • Search Google Scholar
    • Export Citation
  • 81.

    Williams KE, Reeves KR, Billing CB Jr, et al. A double-blind study evaluating the long-term safety of varenicline for smoking cessation. Curr Med Res Opin 2007;23:793801.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 82.

    Anthenelli RM, Morris C, Ramey TS, et al. Effects of varenicline on smoking cessation in adults with stably treated current or past major depression: a randomized trial. Ann Intern Med 2013;159:390400.

    • Search Google Scholar
    • Export Citation
  • 83.

    Prochaska JJ, Hilton JF. Risk of cardiovascular serious adverse events associated with varenicline use for tobacco cessation: systematic review and meta-analysis. BMJ 2012;344:e2856.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 84.

    Svanström H, Pasternak B, Hviid A. Use of varenicline for smoking cessation and risk of serious cardiovascular events: nationwide cohort study. BMJ 2012;345:e7176.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 85.

    Mills EJ, Thorlund K, Eapen S, et al. Cardiovascular events associated with smoking cessation pharmacotherapies: a network meta-analysis. Circulation 2014;129:2841.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 86.

    Sharma A, Thakar S, Lavie CJ, et al. Cardiovascular adverse events associated with smoking-cessation pharmacotherapies. Curr Cardiol Rep 2015;17:554.

  • 87.

    Chelladurai Y, Singh S. Varenicline and cardiovascular adverse events: a perspective review. Ther Adv Drug Saf 2014;5:167172.

  • 88.

    Singh S, Loke YK, Spangler JG, et al. Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis. CMAJ 2011;183:13591366.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 89.

    CDC. Smoking cessation: a report of the surgeon general. Accessed January 12, 2023. Available at https://www.cdc.gov/tobacco/data_statistics/sgr/2020-smoking-cessation/index.html

    • Search Google Scholar
    • Export Citation
  • 90.

    Kotz D, Viechtbauer W, Simpson C, et al. Cardiovascular and neuropsychiatric risks of varenicline: a retrospective cohort study. Lancet Respir Med 2015;3:761768.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 91.

    Serafini A, Crespel A, Velizara R, et al. Varenicline-induced grand mal seizure. Epileptic Disord 2010;12:338.

  • 92.

    Smith SS, McCarthy DE, Japuntich SJ, et al. Comparative effectiveness of 5 smoking cessation pharmacotherapies in primary care clinics. Arch Intern Med 2009;169:21482155.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 93.

    Cahill K, Stevens S, Lancaster T. Pharmacological treatments for smoking cessation. JAMA 2014;311:193194.

  • 94.

    Thomsen T, Villebro N, Møller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev 2014;2014:CD002294.

  • 95.

    Stead LF, Perera R, Bullen C, et al. Nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev 2012;11:CD000146.

  • 96.

    Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev 2018;5:CD000146.

  • 97.

    Fiore MC, Jaén CR, Baker TB, et al. Treating Tobacco Use and Dependence: 2008 Update. US Department of Health and Human Services; 2008.

  • 98.

    Benowitz NL, Jacob P III, Fong I, et al. Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine. J Pharmacol Exp Ther 1994;268:296303.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 99.

    Benowitz NL, Porchet H, Sheiner L, et al. Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clin Pharmacol Ther 1988;44:2328.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 100.

    Benowitz NL, Jacob P III, Savanapridi C. Determinants of nicotine intake while chewing nicotine polacrilex gum. Clin Pharmacol Ther 1987;41:467473.

  • 101.

    Mills EJ, Wu P, Lockhart I, et al. Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals. Tob Induc Dis 2010;8:8.

    • Search Google Scholar
    • Export Citation
  • 102.

    Kimmel SE, Berlin JA, Miles C, et al. Risk of acute first myocardial infarction and use of nicotine patches in a general population. J Am Coll Cardiol 2001;37:12971302.

    • Search Google Scholar
    • Export Citation
  • 103.

    Hubbard R, Lewis S, Smith C, et al. Use of nicotine replacement therapy and the risk of acute myocardial infarction, stroke, and death. Tob Control 2005;14:416421.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 104.

    Meine TJ, Patel MR, Washam JB, et al. Safety and effectiveness of transdermal nicotine patch in smokers admitted with acute coronary syndromes. Am J Cardiol 2005;95:976978.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 105.

    Warren GW, Singh AK. Nicotine and lung cancer. J Carcinog 2013;12:1.

  • 106.

    Martínez-García E, Irigoyen M, González-Moreno O, et al. Repetitive nicotine exposure leads to a more malignant and metastasis-prone phenotype of SCLC: a molecular insight into the importance of quitting smoking during treatment. Toxicol Sci 2010;116:467476.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 107.

    Nishioka T, Luo LY, Shen L, et al. Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability. Br J Cancer 2014;110:17851792.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 108.

    Zhang J, Kamdar O, Le W, et al. Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer. Am J Respir Cell Mol Biol 2009;40:135146.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 109.

    Zhao J, Xin M, Wang T, et al. Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation. Mol Cancer Res 2009;7:19541961.

  • 110.

    Shen T, Le W, Yee A, et al. Nicotine induces resistance to chemotherapy in nasal epithelial cancer. Am J Rhinol Allergy 2010;24:e7377.

  • 111.

    Treviño JG, Pillai S, Kunigal S, et al. Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma. Neoplasia 2012;14:11021114.

    • Search Google Scholar
    • Export Citation
  • 112.

    Maier CR, Hollander MC, Hobbs EA, et al. Nicotine does not enhance tumorigenesis in mutant K-ras-driven mouse models of lung cancer. Cancer Prev Res (Phila) 2011;4:17431751.

    • Search Google Scholar
    • Export Citation
  • 113.

    Murphy SE, von Weymarn LB, Schutten MM, et al. Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis. Cancer Prev Res (Phila) 2011;4:17521760.

    • Search Google Scholar
    • Export Citation
  • 114.

    Stepanov I, Carmella SG, Briggs A, et al. Presence of the carcinogen N′-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products. Cancer Res 2009;69:82368240.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 115.

    Murray RP, Connett JE, Zapawa LM. Does nicotine replacement therapy cause cancer? Evidence from the Lung Health Study. Nicotine Tob Res 2009;11:10761082.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 116.

    Shields PG. Long-term nicotine replacement therapy: cancer risk in context. Cancer Prev Res (Phila) 2011;4:17191723.

  • 117.

    Koegelenberg CF, Noor F, Bateman ED, et al. Efficacy of varenicline combined with nicotine replacement therapy vs varenicline alone for smoking cessation: a randomized clinical trial. JAMA 2014;312:155161.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 118.

    Ramon JM, Morchon S, Baena A, et al. Combining varenicline and nicotine patches: a randomized controlled trial study in smoking cessation. BMC Med 2014;12:172.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 119.

    Hajek P, Smith KM, Dhanji AR, et al. Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? A randomised controlled trial. BMC Med 2013;11:140.

    • Search Google Scholar
    • Export Citation
  • 120.

    Stapleton J, West R, Hajek P, et al. Randomized trial of nicotine replacement therapy (NRT), bupropion and NRT plus bupropion for smoking cessation: effectiveness in clinical practice. Addiction 2013;108:21932201.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 121.

    Jorenby DE, Leischow SJ, Nides MA, et al. A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. N Engl J Med 1999;340:685691.

    • Search Google Scholar
    • Export Citation
  • 122.

    Evins AE, Cather C, Culhane MA, et al. A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. J Clin Psychopharmacol 2007;27:380386.

    • Search Google Scholar
    • Export Citation
  • 123.

    Hughes JR, Stead LF, Hartmann-Boyce J, et al. Antidepressants for smoking cessation. Cochrane Database Syst Rev 2014;2014:CD000031.

  • 124.

    van der Meer RM, Willemsen MC, Smit F, et al. Smoking cessation interventions for smokers with current or past depression. Cochrane Database Syst Rev 2013;2013:CD006102.

    • Search Google Scholar
    • Export Citation
  • 125.

    Hays JT, Hurt RD, Rigotti NA, et al. Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation: a randomized, controlled trial. Ann Intern Med 2001;135:423433.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 126.

    Prescribing information for bupropion hydrochloride sustained-release tablets, for oral use. 2020. Accessed May 5, 2022. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020358s064lbl.pdf

    • Search Google Scholar
    • Export Citation
  • 127.

    Binkhorst L, Mathijssen RH, van Herk-Sukel MP, et al. Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen. Breast Cancer Res Treat 2013;139:923929.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 128.

    Englisch S, Morgen K, Meyer-Lindenberg A, et al. Risks and benefits of bupropion treatment in schizophrenia: a systematic review of the current literature. Clin Neuropharmacol 2013;36:203215.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 129.

    Rose JE, Behm FM. Combination treatment with varenicline and bupropion in an adaptive smoking cessation paradigm. Am J Psychiatry 2014;171:11991205.

    • Search Google Scholar
    • Export Citation
  • 130.

    Rose JE, Behm FM. Combination varenicline/bupropion treatment benefits highly dependent smokers in an adaptive smoking cessation paradigm. Nicotine Tob Res 2017;19:9991002.

    • Search Google Scholar
    • Export Citation
  • 131.

    Ebbert JO, Hatsukami DK, Croghan IT, et al. Combination varenicline and bupropion sr for tobacco-dependence treatment in cigarette smokers: a randomized trial. JAMA 2014;311:155163.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 132.

    Cinciripini PM, Minnix JA, Green CE, et al. An RCT with the combination of varenicline and bupropion for smoking cessation: clinical implications for front line use. Addiction 2018;113:16731682.

    • Search Google Scholar
    • Export Citation
  • 133.

    Barzilai DA, Goodwin MA, Zyzanski SJ, et al. Does health habit counseling affect patient satisfaction? Prev Med 2001;33:595599.

  • 134.

    Conroy MB, Majchrzak NE, Regan S, et al. The association between patient-reported receipt of tobacco intervention at a primary care visit and smokers’ satisfaction with their health care. Nicotine Tob Res 2005; 7(Suppl 1):S2934.

    • Search Google Scholar
    • Export Citation
  • 135.

    Klemp I, Steffenssen M, Bakholdt V, et al. Counseling is effective for smoking cessation in head and neck cancer patients - a systematic review and meta-analysis. J Oral Maxillofac Surg 2016;74:16871694.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 136.

    Lai DT, Cahill K, Qin Y, et al. Motivational interviewing for smoking cessation. Cochrane Database Syst Rev 2010;2010:CD006936.

  • 137.

    Park ER, Perez GK, Regan S, et al. Effect of sustained smoking cessation counseling and provision of medication vs shorter-term counseling and medication advice on smoking abstinence in patients recently diagnosed with cancer. JAMA 2020;324:14061418.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 138.

    Rigotti NA, Clair C, Munafò MR, et al. Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev 2012;5:CD001837.

  • 139.

    Siu AL. Behavioral and pharmacotherapy interventions for tobacco smoking cessation in adults, including pregnant women: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2015;163:622634.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 140.

    Herd N, Borland R. The natural history of quitting smoking: findings from the International Tobacco Control (ITC) Four Country Survey. Addiction 2009;104:20752087.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 141.

    Wang MP, Li WH, Cheung YT, et al. Brief advice on smoking reduction versus abrupt quitting for smoking cessation in Chinese smokers: a cluster randomized controlled trial. Nicotine Tob Res 2017;20:6772.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 142.

    Li WH, Wang MP, Ho KY, et al. Helping cancer patients quit smoking using brief advice based on risk communication: a randomized controlled trial. Sci Rep 2018;8:2712.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 143.

    Hall SM, Humfleet GL, Muñoz RF, et al. Using extended cognitive behavioral treatment and medication to treat dependent smokers. Am J Public Health 2011;101:23492356.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 144.

    Hall SM, Humfleet GL, Muñoz RF, et al. Extended treatment of older cigarette smokers. Addiction 2009;104:10431052.

  • 145.

    Killen JD, Fortmann SP, Schatzberg AF, et al. Extended cognitive behavior therapy for cigarette smoking cessation. Addiction 2008;103:13811390.

  • 146.

    Yalcin BM, Unal M, Pirdal H, et al. Effects of an anger management and stress control program on smoking cessation: a randomized controlled trial. J Am Board Fam Med 2014;27:645660.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 147.

    Matheny KB, Weatherman KE. Predictors of smoking cessation and maintenance. J Clin Psychol 1998;54:223235.

  • 148.

    Senore C, Battista RN, Shapiro SH, et al. Predictors of smoking cessation following physicians’ counseling. Prev Med 1998;27:412421.

  • 149.

    Hughes JR. Effects of abstinence from tobacco: valid symptoms and time course. Nicotine Tob Res 2007;9:315327.

  • 150.

    McLaughlin I, Dani JA, De Biasi M. Nicotine withdrawal. Curr Top Behav Neurosci 2015;24:99123.

  • 151.

    Shiffman S, Patten C, Gwaltney C, et al. Natural history of nicotine withdrawal. Addiction 2006;101:18221832.

  • 152.

    Liebmann EP, Preacher KJ, Richter KP, et al. Identifying pathways to quitting smoking via telemedicine-delivered care. Health Psychol 2019;38:638647.

  • 153.

    Kotsen C, Dilip D, Carter-Harris L, et al. Rapid scaling up of telehealth treatment of tobacco-dependent cancer patients during the COVID-19 outbreak in New York City. Telemed J E Health 2021;27:2029.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 154.

    Civljak M, Stead LF, Hartmann-Boyce J, et al. Internet-based interventions for smoking cessation. Cochrane Database Syst Rev 2013;7:CD007078.

  • 155.

    Bricker JB, Mull KE, McClure JB, et al. Improving quit rates of web-delivered interventions for smoking cessation: full-scale randomized trial of WebQuit.org versus Smokefree.gov. Addiction 2018;113:914923.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 156.

    Stead LF, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database Syst Rev 2005;2005:CD001007.

  • 157.

    Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev 2005;2005:CD001292.

  • 158.

    Hartmann-Boyce J, Lancaster T, Stead LF. Print-based self-help interventions for smoking cessation. Cochrane Database Syst Rev 2014;2014:CD001118.

    • Search Google Scholar
    • Export Citation
  • 159.

    Whittaker R, McRobbie H, Bullen C, et al. Mobile phone-based interventions for smoking cessation. Cochrane Database Syst Rev 2012;11:CD006611.

  • 160.

    Free C, Knight R, Robertson S, et al. Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial. Lancet 2011;378:4955.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 161.

    Abroms LC, Boal AL, Simmens SJ, et al. A randomized trial of Text2Quit: a text messaging program for smoking cessation. Am J Prev Med 2014;47:242250.

  • 162.

    Abroms LC, Padmanabhan N, Thaweethai L, et al. iPhone apps for smoking cessation: a content analysis. Am J Prev Med 2011;40:279285.

  • 163.

    Prutzman YM, Wiseman KP, Grady MA, et al. Using digital technologies to reach tobacco users who want to quit: evidence from the National Cancer Institute’s Smokefree.gov initiative. Am J Prev Med 2021; 60(Suppl 2):S172184.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 164.

    Sampson L, Papadakos J, Milne V, et al. Preferences for the provision of smoking cessation education among cancer patients. J Cancer Educ 2018;33:711.

  • 165.

    Sheeran P, Jones K, Avishai A, et al. What works in smoking cessation interventions for cancer survivors? A meta-analysis. Health Psychol 2019;38:855865.

  • 166.

    Smith SS, Keller PA, Kobinsky KH, et al. Enhancing tobacco quitline effectiveness: identifying a superior pharmacotherapy adjuvant. Nicotine Tob Res 2013;15:718728.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 167.

    Mehnert A, Kuhnt S, Brahler E, et al. Twelve-month prevalence of mental disorders in cancer patients across major tumor entities. J Clin Oncol 2015;33(Suppl):Abstract 9552.

    • Search Google Scholar
    • Export Citation
  • 168.

    Singer S, Das-Munshi J, Brähler E. Prevalence of mental health conditions in cancer patients in acute care--a meta-analysis. Ann Oncol 2010;21:925930.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 169.

    Mehnert A, Brähler E, Faller H, et al. Four-week prevalence of mental disorders in patients with cancer across major tumor entities. J Clin Oncol 2014;32:35403546.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 170.

    Schnoll RA, Malstrom M, James C, et al. Correlates of tobacco use among smokers and recent quitters diagnosed with cancer. Patient Educ Couns 2002;46:137145.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 171.

    Lindson-Hawley N, Thompson TP, Begh R. Motivational interviewing for smoking cessation. Cochrane Database Syst Rev 2015;2015:CD006936.

  • 172.

    Spencer JC, Wheeler SB. A systematic review of Motivational Interviewing interventions in cancer patients and survivors. Patient Educ Couns 2016;99:10991105.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 173.

    Brandon TH, Goniewicz ML, Hanna NH, et al. Electronic nicotine delivery systems: a policy statement from the American Association for Cancer Research and the American Society of Clinical Oncology. J Clin Oncol 2015;33:952963.

    • Search Google Scholar
    • Export Citation
  • 174.

    Bhatnagar A, Whitsel LP, Ribisl KM, et al. Electronic cigarettes: a policy statement from the American Heart Association. Circulation 2014;130:14181436.

  • 175.

    American Cancer Society. American Cancer Society position statement on electronic cigarettes. Accessed January 12, 2023. Available at: https://www.cancer.org/healthy/stay-away-from-tobacco/e-cigarette-position-statement.html

    • Search Google Scholar
    • Export Citation
  • 176.

    Krist AH, Davidson KW, Mangione CM, et al. Interventions for tobacco smoking cessation in adults, including pregnant persons: US Preventive Services Task Force recommendation statement. JAMA 2021;325:265279.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 177.

    Smith DM, Christensen C, van Bemmel D, et al. Exposure to nicotine and toxicants among dual users of tobacco cigarettes and e-cigarettes: Population Assessment of Tobacco and Health (PATH) study, 2013–2014. Nicotine Tob Res 2021;23:790797.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 178.

    Goniewicz ML, Smith DM, Edwards KC, et al. Comparison of nicotine and toxicant exposure in users of electronic cigarettes and combustible cigarettes. JAMA Netw Open 2018;1:e185937.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 179.

    Hajek P, Phillips-Waller A, Przulj D, et al. A randomized trial of e-cigarettes versus nicotine-replacement therapy. N Engl J Med 2019;380:629637.

  • 180.

    Sweet L, Brasky TM, Cooper S, et al. Quitting behaviors among dual cigarette and e-cigarette users and cigarette smokers enrolled in the tobacco user adult cohort. Nicotine Tob Res 2019;21:278284.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 181.

    Hartmann-Boyce J, Lindson N, Butler AR, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev 2022;11:CD010216.

  • 182.

    Shahab L, Goniewicz ML, Blount BC, et al. Nicotine, carcinogen, and toxin exposure in long-term e-cigarette and nicotine replacement therapy users: a cross-sectional study. Ann Intern Med 2017;166:390400.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 183.

    Manzoli L, Flacco ME, Ferrante M, et al. Cohort study of electronic cigarette use: effectiveness and safety at 24 months. Tob Control 2017;26:284292.

  • 184.

    Coleman B, Rostron B, Johnson SE, et al. Transitions in electronic cigarette use among adults in the Population Assessment of Tobacco and Health (PATH) study, waves 1 and 2 (2013–2015). Tob Control 2019;28:5059.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 185.

    Kasza KA, Edwards KC, Kimmel HL, et al. Association of e-cigarette use with discontinuation of cigarette smoking among adult smokers who were initially never planning to quit. JAMA Netw Open 2021;4:e2140880.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 186.

    Kalkhoran S, Glantz SA. E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis. Lancet Respir Med 2016;4:116128.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 187.

    Patil S, Arakeri G, Patil S, et al. Are electronic nicotine delivery systems (ENDs) helping cigarette smokers quit?-Current evidence. J Oral Pathol Med 2020;49:181189.

    • Search Google Scholar
    • Export Citation
  • 188.

    Malas M, van der Tempel J, Schwartz R, et al. Electronic cigarettes for smoking cessation: a systematic review. Nicotine Tob Res 2016;18:19261936.

  • 189.

    Hartmann-Boyce J, McRobbie H, Bullen C, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev 2016;9:CD010216.

  • 190.

    Hartmann-Boyce J, McRobbie H, Butler AR, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev 2021;4:CD010216.

  • 191.

    Brown J, Beard E, Kotz D, et al. Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study. Addiction 2014;109:15311540.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 192.

    American Lung Association. E-cigarette or vaping use-associated lung injury (EVALI). Accessed January 12, 2023. Available at: https://www.lung.org/lung-health-diseases/lung-disease-lookup/evali

    • Search Google Scholar
    • Export Citation
  • 193.

    Layden JE, Ghinai I, Pray I, et al. Pulmonary illness related to e-cigarette use in Illinois and Wisconsin - final report. N Engl J Med 2020;382:903916.

  • 194.

    Werner AK, Koumans EH, Chatham-Stephens K, et al. Hospitalizations and deaths associated with EVALI. N Engl J Med 2020;382:15891598.

  • 195.

    Blount BC, Karwowski MP, Shields PG, et al. Vitamin E acetate in bronchoalveolar-lavage fluid associated with EVALI. N Engl J Med 2020;382:697705.

  • 196.

    Borderud SP, Li Y, Burkhalter JE, et al. Electronic cigarette use among patients with cancer: characteristics of electronic cigarette users and their smoking cessation outcomes. Cancer 2014;120:35273535.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 197.

    Salloum RG, Getz KR, Tan AS, et al. Use of electronic cigarettes among cancer survivors in the U.S. Am J Prev Med 2016;51:762766.

  • 198.

    Fahey MC, Bursac Z, Ebbert JO, et al. Prevalence and correlates of dual tobacco use in cancer survivors. Cancer Causes Control 2019;30:217223.

  • 199.

    Little MA, Klesges RC, Bursac Z, et al. Correlates of smoking status in cancer survivors. J Cancer Surviv 2018;12:828834.

  • 200.

    Akinboro O, Nwabudike S, Elias R, et al. Electronic cigarette use among survivors of smoking-related cancers in the United States. Cancer Epidemiol Biomarkers Prev 2019;28:20872094.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 201.

    McQueen N, Partington EJ, Harrington KF, et al. Smoking cessation and electronic cigarette use among head and neck cancer patients. Otolaryngol Head Neck Surg 2016;154:7379.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 202.

    Correa JB, Brandon KO, Meltzer LR, et al. Electronic cigarette use among patients with cancer: reasons for use, beliefs, and patient-provider communication. Psychooncology 2018;27:17571764.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 203.

    Ussher MH, Taylor AH, Faulkner G. Exercise interventions for smoking cessation. Cochrane Database Syst Rev 2014;2014:CD002295.

  • 204.

    White AR, Rampes H, Liu JP, et al. Acupuncture and related interventions for smoking cessation. Cochrane Database Syst Rev 2014;2014:CD000009.

  • 205.

    Abbot NC, Stead LF, White AR, et al. Hypnotherapy for smoking cessation. Cochrane Database Syst Rev 1998;2:CD001008.

  • 206.

    Barnes J, Dong CY, McRobbie H, et al. Hypnotherapy for smoking cessation. Cochrane Database Syst Rev 2010;10:CD001008.

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 785 785 785
PDF Downloads 537 537 537
EPUB Downloads 0 0 0