HSR23-121: Assessment of Sustained MRD Negativity and Reversion in Real-World Multiple Myeloma Patients Using NGS (clonoSEQ Assay)

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Miao JiangAdaptive Biotechnologies, Seattle, WA

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Tony HewittAdaptive Biotechnologies, Seattle, WA

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Heidi SimmonsAdaptive Biotechnologies, Seattle, WA

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Steve ThuillierAdaptive Biotechnologies, Seattle, WA

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Benjamin EckertAdaptive Biotechnologies, Seattle, WA

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Corresponding Author: Miao Jiang, PhD

Email: mjiang@adaptivebiotech.com
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  • 1.

    Kumar SK, Callander NS, Adekola K, et al. NCCN Clinical Practice Guidelines in Oncology: Multiple Myeloma. Version 3.2023. Accessed November 9, 2022. To view the most recent version, visit https://www.nccn.org

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  • 2.

    Diamond B, Korde N, Lesokhin AM, et al. Dynamics of minimal residual disease in patients with multiple myeloma on continuous lenalidomide maintenance: a single-arm, single-centre, phase 2 trial. Lancet Hematol 2021;8:e422432.

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  • 3.

    San-Miguel J, Avet-Loiseau H, Paiva B, et al. Sustained minimal residual disease negativity in newly diagnosed multiple myeloma and the impact of darat5umumab in MAIA and ALCYONE. Blood 2022;139:492501.

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  • 4.

    Costa LJ, Chhabra S, Medvedova E, et al. Daratumumab, carfilzomib, lenalidomide, and dexamethasone with minimal residual disease response-adapted therapy in newly diagnosed multiple myeloma. J Clin Oncol 2022;40:29012912.

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