Small cell lung cancer (SCLC) accounts for 15% to 25% of all lung cancers. About 98% of SCLC is attributed to cigarette smoking, whereas the remaining cases are presumably caused by environmental or genetic factors. In 2003, an estimated 34,000 new cases of SCLC will have been diagnosed in the United States. SCLC is distinguished from non-small cell lung cancer by its rapid doubling time, high growth fraction, and early development of widespread metastases.
For the most recent version of the guidelines, please visit NCCN.org