Dermatofibrosarcoma Protuberans Clinical Practice Guidelines in Oncology

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Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low-grade sarcoma of fibroblast origin with an incidence rate of 0.8 cases per million persons per year. It rarely metastasizes. However, initial misdiagnosis, prolonged time to correct diagnosis, and large tumor size at the time of diagnosis are common. NCCN's Non-Melanoma Skin Cancer panel has developed a guideline outlining treatment of DFSP to supplement the squamous cell and basal cell skin cancers guidelines. The NCCN Sarcoma Panel also provided expert input in the development of this DFSP guideline.

For the most recent version of the guidelines, please visit

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