NCCN Guidelines® Insights: Older Adult Oncology, Version 1.2021

Featured Updates to the NCCN Guidelines

Authors:
Efrat Dotan Fox Chase Cancer Center;

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Louise C. Walter UCSF Helen Diller Family Comprehensive Cancer Center;

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Ilene S. Browner The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

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Katherine Clifton Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

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Harvey Jay Cohen Duke Cancer Institute;

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Martine Extermann Moffitt Cancer Center;

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Cary Gross Yale Cancer Center/Smilow Cancer Hospital;

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Sumati Gupta Huntsman Cancer Institute at the University of Utah;

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Genevieve Hollis Abramson Cancer Center at the University of Pennsylvania;

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Joleen Hubbard Mayo Clinic Cancer Center;

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Reshma Jagsi University of Michigan Rogel Cancer Center;

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Nancy L. Keating Dana-Farber/Brigham and Women’s Cancer Center;

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Elizabeth Kessler University of Colorado Cancer Center;

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Thuy Koll Fred & Pamela Buffett Cancer Center;

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Beatriz Korc-Grodzicki Memorial Sloan Kettering Cancer Center;

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June M. McKoy Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

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Sumi Misra Vanderbilt-Ingram Cancer Center;

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Dominic Moon UT Southwestern Simmons Comprehensive Cancer Center;

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Tracey O’Connor Roswell Park Comprehensive Cancer Center;

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Cynthia Owusu Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

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Ashley Rosko The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

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Marcia Russell UCLA Jonsson Comprehensive Cancer Center;

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Mina Sedrak City of Hope National Medical Center;

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Fareeha Siddiqui UC San Diego Moores Cancer Center;

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Amy Stella University of Wisconsin Carbone Cancer Center;

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Derek L. Stirewalt Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

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Ishwaria M. Subbiah The University of Texas MD Anderson Cancer Center;

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William P. Tew Memorial Sloan Kettering Cancer Center;

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Grant R. Williams O'Neal Comprehensive Cancer Center at UAB; and

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Liz Hollinger National Comprehensive Cancer Network.

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Giby V. George National Comprehensive Cancer Network.

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Hema Sundar National Comprehensive Cancer Network.

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The NCCN Guidelines for Older Adult Oncology address specific issues related to the management of cancer in older adults, including screening and comprehensive geriatric assessment (CGA), assessing the risks and benefits of treatment, preventing or decreasing complications from therapy, and managing patients deemed to be at high risk for treatment-related toxicity. CGA is a multidisciplinary, in-depth evaluation that assesses the objective health of the older adult while evaluating multiple domains, which may affect cancer prognosis and treatment choices. These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines providing specific practical framework for the use of CGA when evaluating older adults with cancer.

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