Navigating the Jargon of Molecular Testing in Non-Hodgkin Lymphoma

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Eric D. Hsi
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The many different subtypes of non-Hodgkin lymphoma can be distinguished by histopathology, immunophenotype, and underlying genetic abnormalities. Molecular testing is routinely used by pathologists for diagnosis and prognosis, and to aid in guiding therapy selection (targeted or nontargeted). The different tools and techniques used for molecular testing are based on abnormality type and tissue available.

Disclosures: Dr. Hsi has disclosed that he has received grant/research support from AbbVie, Inc. and Eli Lilly and Company, and honoraria from Miltenyi Biotech and Seattle Genetics, Inc.

Correspondence: Eric D. Hsi, MD, Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Avenue, L-30, Cleveland, OH 44195. Email:
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