Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology

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  • 1 Robert H. Lurie Comprehensive Cancer Center of Northwestern University;
  • 2 UCSF Helen Diller Family Comprehensive Cancer Center;
  • 3 University of Michigan Rogel Cancer Center;
  • 4 City of Hope National Medical Center;
  • 5 Vanderbilt-Ingram Cancer Center;
  • 6 Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;
  • 7 Fox Chase Cancer Center;
  • 8 University of Wisconsin Carbone Cancer Center;
  • 9 Huntsman Cancer Institute at the University of Utah;
  • 10 Fred & Pamela Buffett Cancer Center;
  • 11 Moffitt Cancer Center;
  • 12 Mayo Clinic Cancer Center;
  • 13 Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;
  • 14 O'Neal Comprehensive Cancer Center at UAB;
  • 15 Stanford Cancer Institute;
  • 16 Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;
  • 17 University of Colorado Cancer Center;
  • 18 Dana-Farber/Brigham and Women’s Cancer Center;
  • 19 The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;
  • 20 Roswell Park Comprehensive Cancer Center;
  • 21 The University of Texas MD Anderson Cancer Center;
  • 22 Massachusetts General Hospital Cancer Center;
  • 23 UC San Diego Moores Cancer Center;
  • 24 Memorial Sloan Kettering Cancer Center;
  • 25 Abramson Cancer Center at the University of Pennsylvania;
  • 26 The University of Tennessee Health Science Center;
  • 27 The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;
  • 28 Duke Cancer Institute; and
  • 29 National Comprehensive Cancer Network
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Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an advanced stage, outcomes for SBA are worse on average than for other related malignancies, including colorectal cancer. Due to the rarity of this disease, few studies have been done to direct optimal treatment, although recent data have shown that SBA responds to treatment differently than colorectal cancer, necessitating a separate approach to treatment. The NCCN Guidelines for Small Bowel Adenocarcinoma were created to establish an evidence-based standard of care for patients with SBA. These guidelines provide recommendations on the workup of suspected SBA, primary treatment options, adjuvant treatment, surveillance, and systemic therapy for metastatic disease. Additionally, principles of imaging and endoscopy, pathologic review, surgery, radiation therapy, and survivorship are described.

Individual Disclosures for the NCCN Small Bowel Adenocarcinoma Panel

TU1

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