NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019

Featured Updates to the NCCN Guidelines

Authors: Samir Gupta MD 1 , Dawn Provenzale MD, MS 2 , Xavier Llor MD, PhD 3 , Amy L. Halverson MD 4 , William Grady MD 5 , Daniel C. Chung MD 6 , Sigurdis Haraldsdottir MD, PhD 7 , Arnold J. Markowitz MD 8 , Thomas P. Slavin Jr MD 9 , Heather Hampel MS, CGC 10 , Reid M. Ness MD, MPH 11 , Jennifer M. Weiss MD, MS 12 , Dennis J. Ahnen MD 13 , Lee-may Chen MD 14 , Gregory Cooper MD 15 , Dayna S. Early MD 16 , Francis M. Giardiello MD, MBA 17 , Michael J. Hall MD, MS 18 , Stanley R. Hamilton MD 19 , Priyanka Kanth MD, MS 20 , Jason B. Klapman MD 21 , Audrey J. Lazenby MD 22 , Patrick M. Lynch MD, JD 19 , Robert J. Mayer MD 23 , June Mikkelson MS, CGC 24 , Shajan Peter MD 25 , Scott E. Regenbogen MD 26 , Mary A. Dwyer MS, CGC 27 and Ndiya Ogba PhD 27
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  • 1 UC San Diego Moores Cancer Center;
  • 2 Duke Cancer Institute;
  • 3 Yale Cancer Center/Smilow Cancer Hospital;
  • 4 Robert H. Lurie Comprehensive Cancer Center of Northwestern University;
  • 5 Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;
  • 6 Massachusetts General Hospital Cancer Center;
  • 7 Stanford Cancer Institute;
  • 8 Memorial Sloan Kettering Cancer Center;
  • 9 City of Hope National Medical Center;
  • 10 The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;
  • 11 Vanderbilt-Ingram Cancer Center;
  • 12 University of Wisconsin Carbone Cancer Center;
  • 13 University of Colorado Cancer Center;
  • 14 UCSF Helen Diller Family Comprehensive Cancer Center;
  • 15 Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;
  • 16 Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;
  • 17 The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;
  • 18 Fox Chase Cancer Center;
  • 19 The University of Texas MD Anderson Cancer Center;
  • 20 Huntsman Cancer Institute at the University of Utah;
  • 21 Moffitt Cancer Center;
  • 22 Fred & Pamela Buffett Cancer Center;
  • 23 Dana-Farber/Brigham and Women’s Cancer Center;
  • 24 Roswell Park Comprehensive Cancer Center;
  • 25 O'Neal Comprehensive Cancer Center at UAB;
  • 26 University of Michigan Rogel Cancer Center; and
  • 27 National Comprehensive Cancer Network.
Volume/Issue:
Volume 17: Issue 9
Online Publication Date:
Sep 2019
DOI:
https://doi.org/10.6004/jnccn.2019.0044
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Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

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Copyright:
Copyright © 2019 by the National Comprehensive Cancer Network 2019
Page Numbers:
1032–1041
Article Category:
Other
Print Publication Date:
01 Sep 2019
Online Publication Date:
Sep 2019
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