Challenges With the 8th Edition of the AJCC Cancer Staging Manual for Breast, Testicular, and Head and Neck Cancers

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Three experts discussed changes in the 8th edition of the AJCC Cancer Staging Manual and challenges regarding these changes for staging of breast cancer, testicular cancer, and head and neck cancer, respectively. In general, the staging changes for breast cancer and for human papillomavirus–positive oropharyngeal cancer were hailed as improvements, but the changes for testicular cancer were questioned as to their clinical relevance. Better studies are needed to improve staging for human papillomavirus–negative oropharyngeal cancer.

Correspondence: Aysegul A. Sahin, MD, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0085, Room G1.35, Houston TX 77030. Email: asahin@mdanderson.org; Timothy D. Gilligan, MD, Cleveland Clinic Taussig Cancer Institute, 9500 Euclid Avenue, CA-60, Cleveland OH 44195. Email: gilligt@ccf.org; and Jimmy J. Caudell, MD, PhD, Moffitt Cancer Center, 12902 Magnolia Drive, Department of Radiation Oncology, Tampa FL, 33612. Email: jimmy.caudell@moffitt.org
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