1 From Memorial Sloan Kettering Cancer Center; Mayo Clinic Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; Massachusetts General Hospital Cancer Center; Fox Chase Cancer Center; UC San Diego Moores Cancer Center; The University of Texas MD Anderson Cancer Center; Vanderbilt-Ingram Cancer Center; Huntsman Cancer Institute at the University of Utah; University of Colorado Cancer Center; Stanford Cancer Institute; Dana-Farber/Brigham and Women's Cancer Center; Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute; Fred & Pamela Buffett Cancer Center; University of Alabama at Birmingham Comprehensive Cancer Center; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Duke Cancer Institute; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; University of Wisconsin Carbone Cancer Center; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; University of Washington/Seattle Cancer Care Alliance; Moffitt Cancer Center; Roswell Park Comprehensive Cancer Center; University of Michigan Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute; City of Hope Comprehensive Cancer Center; and National Comprehensive Cancer Network.
Natural killer (NK)/T-cell lymphomas are a rare and distinct subtype of non-Hodgkin's lymphomas. NK/T-cell lymphomas are predominantly extranodal and most of these are nasal type, often localized to the upper aerodigestive tract. Because extranodal NK/T-cell lymphomas (ENKL) are rare malignancies, randomized trials comparing different regimens have not been conducted to date and standard therapy has not yet been established for these patients. These NCCN Guidelines Insights discuss the recommendations for the diagnosis and management of patients with ENKL as outlined in the NCCN Guidelines for T-Cell Lymphomas.
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