Re: “Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course”

Authors: Frederick Klauschen MD, PhD, MSc 1 , Hendrik Bläker MD, PhD 1 and Albrecht Stenzinger MD 1
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  • 1 Institute of Pathology, Charité Medical University, Berlin, Germany (FK and HB), Institute of Pathology, University of Heidelberg Medical School, Heidelberg, Germany (AS), Department of Pathology, Center for Integrated Diagnostics, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA (AS)
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    Chapman JS, Asthana S, Cade L. Clinical sequencing contributes to a BRCA-associated cancer rediagnosis that guides an effective therapeutic course. J Natl Compr Canc Netw 2015;13:835845.

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    Travis WD, Brambilla E, Burke AP. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart, 4th ed. Lyon, France: IARC Press: 2014.

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    Klauschen F, Heim D, Stenzinger A. Histological tumor typing in the age of molecular profiling. Pathol Res Pract 2015;211:897900.

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    Stenzinger A, Weichert W, Lennerz JK, Klauschen F. Basket trials: just the end of the first quarter. J Clin Oncol 2015;33:28232524.

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    Klauschen F, Andreeff M, Keilholz U. The combinatorial complexity of cancer precision medicine. Oncoscience 2014;1:504509.

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    Heim D, Budczies J, Stenzinger A. Cancer beyond organ and tissue specificity: next-generation-sequencing gene mutation data reveal complex genetic similarities across major cancers. Int J Cancer 2014;135:23622369.

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    FACT SHEET: Investing in the National Cancer Moonshot [Internet]. [cited 2016 Feb 10]. Available from:

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