Where Does Photodynamic Therapy Fit in the Esophageal Cancer Treatment Jigsaw Puzzle?

Author:
Keyvan Moghissi Presented by Keyvan Moghissi, BSc, MD, MS, FRCS, FETCS, Director and Consultant, Cardiothoracic Surgeon, Yorkshire Laser Centre, East Yorkshire, England.

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 BSc, MD, MS, FRCS, FETCS
Volume/Issue:
Volume 10: Issue Suppl_2
Online Publication Date:
Oct 2012
DOI:
https://doi.org/10.6004/jnccn.2012.0176
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Traditional treatment options for esophageal cancer have centered on the triad of surgery, chemotherapy, and radiotherapy. Although surgery remains the gold standard for operable disease, photodynamic therapy (PDT) is emerging as a valid minimally invasive option for select patients with inoperable disease. Years of experience with PDT for esophageal cancer seem to suggest that it may be particularly useful for treatment of early unresectable lesions, palliation of locally advanced disease, and salvage therapy for stent blockage or local tumor recurrence. Further investigation into the ideal role for PDT, perhaps through a comparative study with other nonsurgical options, may help clarify where it fits in the treatment armamentarium for esophageal cancer.

Correspondence: Keyvan Moghissi, MD, Yorkshire Laser Centre, Goole & District Hospital, Woodlands Avenue, Goole, East Yorkshire DN14 6RX England. E-mail: kmoghissi@yorkshirelasercentre.org

Dr. Moghissi has disclosed that he has no financial interests, arrangements, commercial interest conflicts, or affiliations with the manufacturers of any products discussed in this article or their competitors.

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Print ISSN:
1540-1405
Online ISSN:
1540-1413
Publisher:
National Comprehensive Cancer Network
Cover Journal of the National Comprehensive Cancer Network
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Copyright:
Copyright © 2012 by the National Comprehensive Cancer Network 2012
Article Category:
Research Article
Print Publication Date:
01 Oct 2012
Online Publication Date:
Oct 2012

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